Research and Development

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Researchers develop algorithm able to identify antidepressant suitability

July 18, 2018 Research and Development McLean, algorithm, antidepressants, research

A study published by researchers at McLean Hospital in Belmont, Massachusetts has led to the development of a statistical algorithm …
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AbbVie and Mylan reach US marketing agreement for Humira biosimilar

July 18, 2018 Research and Development, Sales and Marketing AbbVie, Humira, Mylan, US, pharma

AbbVie and Mylan have announced that they have both signed a licensing agreement for the former’s proposed biosimilar version of …
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Renowned cancer researcher leaves ICR over bullying allegations

July 17, 2018 Research and Development

Leading geneticist and cancer researcher, Nazneen Rahman CBE, has resigned from her position as head of Genetics and Epidemiology at …
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Silence Therapeutics appoints ex-Akari CEO in top position

July 17, 2018 Business Services, Manufacturing and Production, Medical Communications, Research and Development, Sales and Marketing Akari, CEO, Sanofi, Silence Therapeutics, zealand

Silence Therapeutics has appointed Dr David Horn Solomon as its new Chief Executive Officer (CEO), effective immediately. Solomon will head …
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Researchers successfully minimise diabetes drug side-effects in animal models

July 17, 2018 Manufacturing and Production, Research and Development FDA, diabetes, pharma, type 2 diabetes

Researchers at the University of Pennsylvania and Syracuse University have modified a key ingredient of current diabetes drugs to produce …

Roche flu drug proves efficacy at Phase 3, but enough to beat Tamiflu generics?

July 17, 2018 Manufacturing and Production, Research and Development Roche, Tamiflu, baloxavir marboxil, flu, influenza, pharma

Roche is celebrating the news that its investigational influenza drug baloxavir marboxil performed well at Phase 3, meeting its primary …
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J&J stops Invokana trial early after success in kidney disease and type 2 diabetes

July 17, 2018 Manufacturing and Production, Research and Development J&J, JJ, Janssen, Johnson & Johnson, invokana, kidney disease, pharma, renal, type 2 diabetesm diabetes

Johnson & Johnson and research arm Janssen have taken the decision to terminate a Phase 3 trial evaluating the efficacy …
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Recruitment and retention: How can we do better?

July 16, 2018 Business Services, Manufacturing and Production, Medical Communications, Research and Development, Sales and Marketing clinical trials, feature, patient recruitment, patients, pharma

In pharma R&D, data is king, but consistent struggles with patient retention is undermining the integrity of clinical findings. Matt …
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Takeda’s Ninlaro clears Phase 3 endpoint as maintenance therapy in multiple myeloma

July 12, 2018 Medical Communications, Research and Development Ninlaro, Takeda, multiple myeloma, pharma

After making headlines with its mammoth deal to acquire Shire earlier this year, Takeda has emerged with new Phase 3 …
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Top Ten most popular articles on Pharmafile.com this week

July 12, 2018 Business Services, Manufacturing and Production, Medical Communications, Research and Development, Sales and Marketing EMA, Pfizer, Sanofi, Trump, top 10

In the week leading up to Donald Trump’s visit to the United Kingdom, the news has been dominated by the …
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Otsuka snaps up Visterra in $430 million deal

July 12, 2018 Research and Development, Sales and Marketing Otsuka, Visterra, acquisition, pharma

Otsuka Pharmaceutical has announced it has reached a definitive, board-approved agreement with Visterra to acquire the latter company in an …

AbbVie and Janssen announce failure of cancer drug Imbruvica in Phase 3 trial

July 12, 2018 Research and Development AbbVie, Cancer, FDA, Janssen, approval

AbbVie and Janssen have announced that Imbruvica (ibrutinib) failed to achieve the primary endpoint in a late-stage study assessing its …
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Celgene and Acceleron’s blood disorder drug smashes endpoints at Phase 3

July 11, 2018 Research and Development Acceleron, Celgene, beta-thalassemia, luspatercept, pharma

Celgene and Acceleron have lifted the curtain on new Phase 3 data for their erythroid maturation agent (EMA) luspatercept, confirming …
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UK Government announces £10m antimicrobial resistance research competition

July 11, 2018 Research and Development 10 million, antimicrobial, competition, government, resistance

The UK Government’s Department of Health and Social Care has announced the launch of a £10 million research competition aimed …
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EMA survey identifies gaps in pharma industry’s preparedness for Brexit

July 11, 2018 Research and Development CAPS, EEA, EMA, brexit, preparedness

An EMA survey has identified gaps in the pharmaceutical industry’s preparedness for Brexit, finding that only 58% of market authorisation …
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