Dame Sally Davies says medicinal cannabis legalisation has opened Pandora’s Box

March 20, 2019
Research and Development

England’s Chief Medical Officer (CMO), Dame Sally Davies has said the legalisation of medicinal cannabis has “opened a Pandora’s Box,” …

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Breast cancer mortality rates fall faster in Britain than elsewhere in Europe

March 19, 2019
Manufacturing and Production, Research and Development Cancer, EU, Europe, France, Italy, Poland, UK, breast cancer, german, oncology

Death rates from breast cancer are falling faster in Britain than in any of the other six most populous countries …

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AZ’s Farxiga reduces major adverse cardiovascular event risk in type 2 diabetes, new data shows

March 19, 2019
Manufacturing and Production, Research and Development AstraZeneca, cardiovascular, farxiga, pharma

AstraZeneca has lifted the curtain on new Phase 3 data for its sodium-glucose co-transporter 2 (SGLT2) inhibitor Farxiga (dapagliflozin), reinforcing …

Shortage of cancer doctors puts NHS patients at risk

March 19, 2019
Manufacturing and Production, Research and Development Cancer, NHS, oncologists, radiology, shortfall, staff

A shortage of cancer doctors is putting patients at risk, according to a new report from the Royal College of …

allergan

FDA approves first paediatric treatment for intra-abdominal and urinary tract infections in over 10 years

March 19, 2019
Manufacturing and Production, Sales and Marketing Allergan, Avycaz, FDA, pharma

Allergan has revealed that Avycaz (ceftazidime and avibactam) has been awarded an expansion of its label by the FDA to include …

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Daiichi Sankyo show positive results for atrial fibrillation treatment Lixiana

March 18, 2019
Manufacturing and Production, Research and Development Daiichi Sankyo, Lixiana, pharma, vitamin K antagonist

Japanese firm Daiichi Sankyo has announced positive results of the first randomised controlled trial of uninterrupted Lixiana (edoxoban) in atrial …

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Patient Experience: Living with two rare diseases

March 18, 2019
Business Services, Manufacturing and Production, Medical Communications, Research and Development, Sales and Marketing Wyburn-Mason Syndrome, acromegaly, feature, patient experience, pharma, rare disease

Dan Jeffries was diagnosed with the ultra-rare condition Wyburn-Mason syndrome at a young age, leaving him blind in one eye. …

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Allergy Therapeutics’ adjuvanted birch allergoid drug shocks with Phase 3 failure

March 18, 2019
Research and Development, Sales and Marketing allergy, allergy therapeutics, pharma, trial failure

UK-based biotech firm Allergy Therapeutics has been left disappointed after it became evident that its adjuvanted birch allergoid product failed …

NHS struggles to meet targets as more demand for services grows

March 18, 2019
Sales and Marketing A&E, NHS, hospitals

The NHS is struggling to meet targets as the health service is being used by more patients than ever before, …

NICE to set out new opioid prescription guidelines for GPs

March 18, 2019
Sales and Marketing GPs, NICE, addiction, addictive drugs, opioids, prescription drugs, withdrawal

NICE is set to develop new guidelines for GPs and healthcare professionals setting out rules for doctors regarding opioids and …

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Sanofi and Regeneron’s Praluent approved in Europe to reduce CV risk

March 18, 2019
Research and Development, Sales and Marketing Regeneron, Sanofi, cardiovascular, heart, praluent

Sanofi and Regeneron’s Praluent (alirocumab) has been awarded approval by the European Commission, it has emerged, as a therapy to …

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Purdue Pharma vow not to profit from fast tracked opioid overdose antidote

March 18, 2019
Sales and Marketing FDA, OxyContin, Purdue Pharma, nalmefene hydrochloride, opioids

The FDA has granted OxyContin drugmaker Purdue Pharma, fast track designation for opioid overdose antidote nalmefene hydrochloride (HCl) injection. However, …

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Merck KGaA enters drug discovery partnership with AI firm Itkos

March 15, 2019
Medical Communications, Research and Development AI, Merck, Merck KGaA, drug discovery, pharma

Merck KGaA and artificial intelligence (AI) firm Iktos have entered into a partnership, the pair have announced, to leverage the …

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National Cancer Institute Director Ned Sharpless to become interim FDA Commissioner

March 15, 2019
Business Services, Manufacturing and Production, Medical Communications, Research and Development, Sales and Marketing

Following the surprise resignation of current FDA Commissioner Dr Scott Gottlieb a week earlier, Dr Norman ‘Ned’ Sharpless, Director of …

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Sandoz CEO Richard Francis to step down

March 15, 2019
Business Services, Manufacturing and Production, Medical Communications, Research and Development, Sales and Marketing

Richard Francis is set to step down his role as Chief Executive of Novartis’ generics arm Sandoz after five years’ …

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Roche scores two EU approvals in haemophilia and rare autoimmune disease

March 15, 2019
Medical Communications EC, EU, Europe, Roche, haemophilia, rare diseases

The European Commission (EC) has approved Roche’s haemophilia treatment Hemlibra (emicizumab). The approval comes as the EC approved Roche’s MabThera …

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MSD’s Keytruda/chemo combo nabs EU approval in first-line metastatic squamous lung cancer

March 15, 2019
Medical Communications, Sales and Marketing Cancer, MSD, NSCLC, keytruda, lung cancer, pharma

MSD’s anti-PD-L1 therapy Keytruda (pembrolizumab) has been awarded marketing authorisation in Europe for the first-line treatment of adult patients with …

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Top Ten most popular articles on Pharmafile.com this week!

March 15, 2019
Business Services, Manufacturing and Production, Medical Communications, Research and Development, Sales and Marketing Acadia Pharmaceuticals, FDA, Sandoz, brexit, genomics, pharma, pharmacovigilance, top 10

The US Department of Justice has launched an investigation into the sales and marketing practices of San Diego firm Acadia …

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Pfizer CEO Ian Read’s pay packet cut from $27.9m to $19.5m

March 15, 2019
Medical Communications CEO, Ian Read, Pfizer, compensation, pay packet, salary

Ian Read has seen his total compensation cut from a sum of $27.9 million in 2018 to $19.5 million this …

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Roche and Chugai’s Hemlibra scoops up EU approval in the prevention of severe haemophilia A without factor VIII inhibitors

March 14, 2019
Sales and Marketing Chugai, Hemlibra, Roche, haemophilia, pharma

Roche has announced along with its partner Chugai that Hemlibra (emicizumab) has secured approval from the European Commission as a …

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