Research and Development

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Novartis hid faulty data from FDA over $2.1 million gene therapy Zolgensma

August 7, 2019 Research and Development AveXis, FDA, Novartis, Zolgensma, gene therapy, pharma

Novartis hid faulty data from the FDA until their drug was approved, according to a statement from Dr Peter Marks, …
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Troy Robinson promoted to managing director of Chugai Pharma Europe

August 6, 2019 Business Services, Manufacturing and Production, Medical Communications, Research and Development, Sales and Marketing

Troy Robinson has been taken on as the new managing director of Chugai Pharma Europe. Mike Crosher will succeed him …
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Lilly’s Emgality smashes all Phase 3 endpoints in migraine sub-population

August 6, 2019 Manufacturing and Production, Research and Development Eli Lilly, Emgality, migraine, pharma

New Phase 3 data have been revealed on Eli Lilly’s Emgality (galcanezumab-gnlm), detailing its success in meeting all of its …
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Living with a rare genetic neurodevelopmental disorder

August 5, 2019 Business Services, Manufacturing and Production, Medical Communications, Research and Development, Sales and Marketing KAT6A, feature, patient experience, pharma, rare disease

Vaila Morrison’s daughter Eilidh was born with the ultra-rare condition KAT6A. As a designer and architect by profession, Vaila told …
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Additional data for Boehringer’s Giotrif combo shows strong overall survival benefit in lung cancer sub-population

August 5, 2019 Research and Development, Sales and Marketing Boehringer Ingelheim, Cancer, giotrif, lung cancer, pharma

German firm Boehringer Ingelheim has released new interim data from a real-world evidence study investigating the efficacy of Giotrif/Gilotrif (afatinib) …

Pollen spores could be used to protect potent, ocean-dwelling antibiotics in fighting antibiotic resistant superbugs

August 5, 2019 Research and Development, Sales and Marketing AMR, Antibiotics, MRSA, club moss, pharma, pollen, spores

Spores from a plant called the common club moss (Lycopodium clavatum) could be used to protect light-sensitive antibiotics, that are …
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Top Ten most popular articles on Pharmafile.com this week!

August 2, 2019 Business Services, Manufacturing and Production, Medical Communications, Research and Development, Sales and Marketing

Pfizer dominated the headlines this week as the US firm closed its $9.8 billion merger with GSK and announced that …
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Novartis’ Kisqali reinforces overall survival benefit in postmenopausal HR+/HER2- breast cancer

August 1, 2019 Research and Development Cancer, Kisqali, Novartis, breast cancer, pharma

New Phase 3 evidence has emerged on the efficacy of Novartis’ Kisqali (ribociclib) in combination with AstraZeneca’s Faslodex (fulvestrant) in …
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MSD to bring over 400 new jobs to North Carolina with two site expansions

July 31, 2019 Manufacturing and Production, Research and Development MSD, US, pharma

MSD has announced a $650 million expansion of its existing facilities in North Carolina – a move which is bring …
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Biogen & Alkermes’ multiple sclerosis drug proves “statistically superior” to Tecfidera at Phase 3

July 31, 2019 Research and Development Alkermes, Biogen, multiple sclerosis, pharma

Biogen and Alkermes have unveiled new Phase 3 data for diroximel fumarate, comparing the adequacy of the therapy to Biogen’s …
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Lilly’s Verzenio combo shows additional breast cancer survival benefit in new Phase 3 data

July 31, 2019 Research and Development Cancer, Eli Lilly, Verzenio, breast cancer, pharma

Eli Lilly has revealed new Phase 3 data on its CDK4 & 6 inhibitor Verzenio (abemaciclib), demonstrating its efficacy in …
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Bayer and Orion’s Nubeqa secures FDA approval in non-metastatic castration-resistant prostate cancer

July 31, 2019 Research and Development, Sales and Marketing Bayer, Cancer, Nubeqa, orion, pharma, prostate cancer

The FDA has awarded approval under its Priority Review pathway to Nubeqa (darolutamide) for the treatment of non-metastatic castration-resistant prostate …
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Cigarette smoke causes superbug to become more drug resistant, study shows

July 30, 2019 Research and Development AMR, MRSA, cigarettes smoke, drug resistance, pharma, smoking

Cigarette smoke can make certain strains of the bacteria Methicillin-resistant Staphylococcus aureus (MRSA) more resistant to antibiotics, according to a …
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MSD’s Keytruda combo hits primary endpoint at Phase 3 in triple-negative breast cancer

July 30, 2019 Manufacturing and Production, Research and Development Cancer, MSD, breast cancer, keytruda, pharma

MSD’s blockbuster anti-PD-L1 immunotherapy Keytruda (pembrolizumab) has impressed in newly released Phase 3 data; the company announced that, when combined …
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