evidence-based medicine
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Healthcare, politics and the NHS
November 24, 2010Research and Development Academy of Medical Sciences, Les Roes, NHS, clinical trials, clinical trials governance, evidence-based medicine
I have just participated in a consultation by the Academy of Medical Sciences on the regulation and governance of clinical …
Health outcomes – does anything else matter?
October 27, 2010Research and Development Les Rose, evidence-based medicine, healthcare outcomes, randomised controlled trials
So the mould of British politics has been broken, and we now have a government with probably a broader range …
Online multidisciplinary library goes live
August 12, 2010Medical Communications Cochrane, Wiley, Wiley-Blackwell, evidence-based medicine
A new online resource offering access to one of the world’s most extensive multidisciplinary collections of resources for health, physical …
Digital Pharma: NICE launches mobile evidence service
July 9, 2010Medical Communications Digital Pharma blog, NHS Evidence, NICE, evidence-based medicine
NICE has launched a mobile version of its online clinical evidence portal NHS Evidence. The beta version of the service …
Emerging confidence
October 2, 2008Research and Development, Sales and Marketing emerging markets, evidence-based medicine
The wisdom that emerging markets are vital to the pharmaceutical and biotechnology industry’s future has become a lot more conventional …
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