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Research and Development

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Purdue Pharma settle Oklahoma lawsuit for $270 million

March 26, 2019 Research and Development Oklahoma, OxyContin, Purdue Pharma, opioid crisis, oxycodone

OxyContin drugmaker Purdue Pharma has agreed to pay nearly $270 million to the state of Oklahoma, in order to settle …
News
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Novo Nordisk’s oral semaglutide outclasses Januvia with new data in type 2 diabetes

March 26, 2019 Manufacturing and Production, Research and Development Novo Nordisk, Ozempic, diabetes, pharma, type 2 diabetes

Novo Nordisk has revealed new dose-specific Phase 3a data for its glucagon-like peptide-1 (GLP-1) analogue oral semaglutide, indicating that the …
News
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Aimmune’s peanut allergy therapy closes in on approval with promising Phase 3 data

March 26, 2019 Manufacturing and Production, Research and Development AR101, Aimmune, allergy, pharma

Aimmune Therapeutics is gearing up for regulatory review of its investigational food allergy therapy AR101 following the release of new …
News
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Conducting internal investigations within a pharmaceutical business

March 25, 2019 Business Services, Manufacturing and Production, Medical Communications, Research and Development, Sales and Marketing Reed Smith, feature, internal investigations, pharma

Though often necessary, internal investigations are seldom smooth or easy. Rosanne Kay, Partner at law firm Reed Smith, outlines a …
Feature
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Top Ten most popular articles on Pharmafile.com this week!

March 22, 2019 Business Services, Manufacturing and Production, Medical Communications, Research and Development, Sales and Marketing AstraZeneca, Biogen, Eisai, FDA, Merck, NICE, Pfizer, Roche, Sandoz

This week was a bad week for clinical trials. While the FDA put Roche and AbbVie’s multiple myeloma trial on …
News

Breathing life into COPD research

March 21, 2019 Business Services, Manufacturing and Production, Medical Communications, Research and Development, Sales and Marketing COPD, GSK, feature

Alison Hollands, Vice President, Respiratory, UK Pharmaceuticals at GlaxoSmithKline, addresses the importance of implementing the latest approaches to treating COPD …
Feature
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Biogen and Eisai discontinue Phase 3 Alzheimer’s trial

March 21, 2019 Research and Development Alzheimer's, Biogen, CNS, Eisai, mental health

Biogen and Eisai have announced their decision to discontinue a Phase 3 trial looking into the efficacy and safety of …
News
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Celgene inks drug discovery deal worth at least £25m with AI firm Exscientia

March 21, 2019 Research and Development Celgene, Exscientia, drug discovery, pharma

Celgene has entered into a new three-year partnership with British artificial intelligence and drug discovery firm Exscientia to the value …
News
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Antiepileptics increase the risk of pneumonia in people with Alzheimer’s disease

March 21, 2019 Research and Development Alzheimer's, R&D, adverse events, antiepileptic drugs, epilepsy, pneumonia

Antiepileptic drugs increase the risk of pneumonia in people living with Alzheimer’s disease, according to research from the University of …
News

Roche’s Tecentriq chalks up another FDA approval, this time in first-line extensive-stage small cell lung cancer

March 20, 2019 Research and Development, Sales and Marketing FDA, Roche, lung cancer, pharma, tecentriq

Roche has secured another US approval for its immunotherapy Tecentriq (atezolizumab), as the FDA reveals its approval of the drug …
News
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FDA puts multiple myeloma trial on hold after patient deaths

March 20, 2019 Research and Development AbbVie, FDA, Roche, clinical trials, multiple myeloma

The FDA has placed a partial clinical hold on studies of multiple myeloma treatment Venclexta/Venclyxto (venetoclax) following a number of …
News

FDA approves first-ever postpartum depression therapy: Sage Therapeutics’ Zulresso

March 20, 2019 Research and Development, Sales and Marketing FDA, Sage Therapeutics, depression, pharma, postpartum depression

The FDA has announced its decision to approve Sage Therapeutics’ intraveneous injection Zulresso (brexanolone), marking the first authorisation of a …
News

Pfizer and Merck discontinue Phase 3 avelumab ovarian cancer trial

March 20, 2019 Research and Development Merck KGaA, Pfizer, javelin, oncology, ovarian cancer

Pfizer and Merck KGaA have chosen to discontinue the Phase 3 JAVELIN trial looking into avelumab in combination with chemotherapy …
News

Dame Sally Davies says medicinal cannabis legalisation has opened Pandora’s Box

March 20, 2019 Research and Development

England’s Chief Medical Officer (CMO), Dame Sally Davies has said the legalisation of medicinal cannabis has “opened a Pandora’s Box,” …
News
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Breast cancer mortality rates fall faster in Britain than elsewhere in Europe

March 19, 2019 Manufacturing and Production, Research and Development Cancer, EU, Europe, France, Italy, Poland, UK, breast cancer, german, oncology

Death rates from breast cancer are falling faster in Britain than in any of the other six most populous countries …
News
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