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Research and Development

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Scorpion venom added to CAR-T therapy increases efficacy in brain cancer, research shows

March 6, 2020 Medical Communications, Research and Development CAR-T, Cancer, brain cancer, glioblastoma, pharma

Chimeric antigen receptor T cell (CAR-T) therapy has gained much traction and attention in the past years for its innovative …
News
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Phase 3 failure for AstraZeneca’s Imfinzi combo in unresectable metastatic bladder cancer

March 6, 2020 Medical Communications, Research and Development AstraZeneca, Cancer, Imfinzi, bladder cancer, pharma, trial failure

New Phase 3 has been released by AstraZeneca, showing that the PD-L1 inhibitor Imfinzi (durvalumab), when combined with tremelimumab, failed …
News
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New study calculates median drug development costs at circa $1 billion

March 5, 2020 Manufacturing and Production, Research and Development, Sales and Marketing drug development, drug prices, pharma

New research has pinned a concrete figure on the perennial industry question: how much does it cost to bring a …
News
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Positive CHMP approval for Takeda’s Alunbrig in ALK+ advanced non-small lung cancer

March 4, 2020 Research and Development CHMP, EMA, Takeda, lung cancer, pharma

Takeda’s Alunbrig (brigatinib) has been recommended for approval by the European Medicines Agency’s (EMA) Committee for Medicinal Products for Human …
News
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Big Pharma more profitable than most public firms

March 4, 2020 Research and Development Big Pharma, US Pharma, drug prices, drug regulations, regulations

Large pharmaceutical companies make a much larger profit than most other public companies, according to a new study. The research …
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India reducing API exports due to coronavirus threatening global supply chain

March 4, 2020 Research and Development APIs, Active Pharmaceuticals Ingredients, Big Pharma, Chinese Coronavirus, Wuhan Coronavirus, coronavirus

India is set to reduce exports of active pharmaceutical ingredients (APIs) until further notice, due to fears of internal drug …
News
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NICE recommends avatrombopag to treat thrombocytopenia in chronic liver disease

March 4, 2020 Research and Development Avatrombopag, NHS, NICE, UK, chronic liver disease

UK drug watchdog NICE has announced its final draft guidance recommending avatrombopag for routine use on the NHS in England …
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Trump meets pharmaceutical executives to discuss COVID-19 vaccine

March 4, 2020 Research and Development COVID-19, Chinese Coronavirus, Trump, Wuhan Coronavirus, coronavirus

President Trump has met with several representatives of the top pharmaceutical companies to discuss progress being made on a coronavirus …
News
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Funding overview for the pharmaceutical industry and outlook for 2020

March 2, 2020 Business Services, Manufacturing and Production, Medical Communications, Research and Development, Sales and Marketing 2020, M&A, MA, feature, mergers & acquisitions, opinion, pharma

This article was originally published in the January/February 2020 issue of Pharmafocus.With the advent of a New Year, Michael Jewell, …
Feature
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Top Ten most popular articles on Pharmafile.com this week

February 28, 2020 Business Services, Manufacturing and Production, Medical Communications, Research and Development, Sales and Marketing Chinese Coronavirus, Johnson and Johnson, Wuhan Coronavirus, coronavirus

The coronavirus continues to spread across the globe as the US launch their first trials for Gilead’s ebola drug remdesivir …
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The March 2020 issue of Pharmafocus is available to read free online now!

February 27, 2020 Business Services, Manufacturing and Production, Medical Communications, Research and Development, Sales and Marketing England, Pharmafocus, UK, mumps, pharma, pharmacovigilance, type 2 diabetes

The latest monthly edition of Pharmafocus, the March issue, is available to read for free online now! The coronavirus continues …
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Female participation up in 2019 US clinical trials, but minority representation down

February 27, 2020 Medical Communications, Research and Development FDA, clinical trials, pharma

The FDA’s Drugs Trials Snapshots 2019 report has been released, clarifying the demographic distribution of participants who were included in …
News
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US Judge rules that a decade of unpublished trial results must be made public

February 27, 2020 Medical Communications, Research and Development FDA, US, clinical trials, pharma

A federal judge in New York’s Southern District has ruled that 10 years of unpublished clinical trial data must now …
News
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First US coronavirus trial launched into Gilead’s remdesivir

February 26, 2020 Research and Development FDA, Gilead, US, coronavirus, pharma

The first US clinical trial investigating a treatment for the COVID-19 coronavirus has been launched by the US National Institute …
News
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Takeda acquires PvP Biologics after successful Phase 1 study of Celiac Disease treatment

February 26, 2020 Research and Development Celiac, PvP, Takeda, phase 1, phase III

Takeda has acquired PvP Biologics following the conclusion of a Phase 1 study of the investigational medicine TAK-062 for the …
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