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Drug safety: EudraVigilance and an evolving system

March 12, 2018 Business Services, Manufacturing and Production, Medical Communications, Research and Development, Sales and Marketing drug safety, pharma, pharmacovigilance

The importance of drug safety is back in the news due to sodium valproate and Ben Hargreaves examines how the …
Feature
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AstraZeneca’s Brilinta proves safety in heart attack patients at Phase 3

March 12, 2018 Research and Development, Sales and Marketing AstraZeneca, Brilinta, heart attack

AstraZeneca has revealed new Phase 3 data on its direct-acting P2Y12 receptor antagonist Brilinta (ticagrelor) at the American College of …
News
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Martin Shkreli sentenced to seven years in jail for securities fraud

March 12, 2018 Business Services, Manufacturing and Production, Medical Communications, Research and Development, Sales and Marketing Martin Shkreli, pharma

Three years after he became “the most hated man in America” overnight for jacking up the price of life-saving HIV-related …
News
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Sanofi and Regeneron reveal strong data and a price drop for Praluent

March 12, 2018 Research and Development, Sales and Marketing Regeneron, Sanofi, pharma, praluent

Sanofi and Regeneron have revealed strong new data for its PCSK9 inhibitor Praluent showing the first-ever reduction in deaths within …
News
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Top Ten most popular articles on Pharmafile.com this week

March 9, 2018 Business Services, Manufacturing and Production, Medical Communications, Research and Development, Sales and Marketing AbbVie, Biogen, Celgene, EMA, Gilead, HIV, Herceptin, Japan, NHS, Ontruzant, Sanofi, opioid crisis, opioids, pharma, real world data, top ten, zinbryta

After a particularly jarring bout of cold weather and snow, we may just have seen off the worst of winter …
News
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Convert secures €13.6m grant to develop targeted chemo for oxygen-deprived tumours

March 9, 2018 Medical Communications, Research and Development Belgium, Cancer, Convert pharma, chemotherapy, pharma

Belgium’s Convert Pharmaceuticals has secured a €13.6 million grant for initial development efforts on a new targeted chemotherapy drug which …
News
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VBL Therapeutics’ shares plummet on Phase 3 glioblastoma failure

March 9, 2018 Medical Communications, Research and Development VBL, VBL Therapeutics, glioblastoma, pharma, trial failure

Israeli drug development firm VBL Therapeutics has been left reeling after it announced that its lead oncology product ofranergene obadenovec, …
News
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Opioids are no more effective than common painkillers, study reveals

March 8, 2018 Medical Communications, Research and Development US, opioid crisis, opioids, pharma

A team of researchers at the Minneapolis Veterans Affairs Health Care System has found that, for all their risks, opioids …
News
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EvoTec to command vast Sanofi resources in infectious disease R&D partnership

March 8, 2018 Research and Development, Sales and Marketing Evotec, Sanofi, infectious disease, infective disease, pharma

Sanofi has announced it is to team up with biotech drug discovery specialist EvoTec to leverage a new open innovation …
News

FDA greenlights alternative therapy for multidrug-resistant HIV patients

March 7, 2018 Research and Development, Sales and Marketing HIV, Theratechnologies, Trogarzo, pharma

Theratechnologies has revealed that Trogarzo has received approval from the FDA as a treatment of HIV-1 in patients with multidrug-resistant …
News
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Former Sanofi exec accused of sexting and indecent exposure demands €1.2m

March 7, 2018 Research and Development, Sales and Marketing Sanofi, pharma

A former Sanofi executive fired for sexting, indecent exposure and other alleged sexual harassment charges has been demanding up to …
News
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Study reveals “concerning” low standards of type 2 diabetes drugs in India

March 7, 2018 Research and Development India, diabetes, pharma, regulatory, type 2 diabetes

In what they believe is the first study of its kind, a team of researchers at the University of Massachusetts …
News
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Japan saves record $12.2bn in 2017 through greater generic use

March 7, 2018 Research and Development, Sales and Marketing Japan, generics, keytruda, opdivo, pharma

Through a concerted shift from branded drugs to generic equivalents as a means to lower prescription costs, Japan is estimated …
News

FDA authorises first direct-to-consumer test for BRCA mutations, with caveats

March 6, 2018 Research and Development, Sales and Marketing 23andME, BRCA, Cancer, FDA, breast cancer, ovarian cancer, pharma

The FDA has given its authorisation to the first ever direct-to-consumer (DTC) test to identify three BRCA gene mutations which …
News
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Blood test could predict treatment effectiveness months earlier in breast cancer

March 6, 2018 Manufacturing and Production, Research and Development Cancer, ICR, Institute of Cancer Research, Royal Marsden NHS Foundation Trust, breast cancer, palbociclib, pharma

A team of scientists at The Institute of Cancer Research in London and The Royal Marsden NHS Foundation Trust have …
News
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