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Research and Development

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Opdivo + cabiralizumab combo falls flat in advanced pancreatic cancer

February 19, 2020 Research and Development Bristol-Myers Squibb, Five Prime Therapeutics, Pancreatic cancer, cabiralizumab, opdivo, pharma

Five Prime Therapeutics and Bristol-Myers Squibb have confirmed that their randomised Phase 2 trial investigating the efficacy of the former’s …
News
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Women who take statins could be less likely to develop ovarian cancer, study finds

February 19, 2020 Research and Development, Sales and Marketing Cancer, Cancer Research UK, cholesterol, ovarian cancer, statins

A study by Cancer Research UK has found that women who take statins, drugs that lower cholesterol, are less likely …
News
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Janssen shows off Phase 3b interim data for Stelara in Crohn’s disease

February 18, 2020 Manufacturing and Production, Research and Development Crohn’s disease, Janssen, Stelara, crohn's disease, pharma

Janssen has revealed new interim Phase 3b data from a study investigating the efficacy of Stelara (ustekinumab) in the treatment …
News

Patient Experience: Living with multiple rare diseases

February 17, 2020 Business Services, Manufacturing and Production, Medical Communications, Research and Development, Sales and Marketing feature, patient experience, pharma, rare disease

Carole Scrafton discusses her experience living with Ehlers-Danlos syndrome alongside other rare conditions that have manifested throughout her life, and …
Feature
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Lawsuit against FDA claims Bernie Sanders played role in approval of rival drug

February 17, 2020 Research and Development, Sales and Marketing Bernie, Bernie Sanders, Catalyst Pharmaceuticals, FDA, TRUMP FDA, US FDA

Catalyst Pharmaceutical is attempting to show in court that pressure from US Senator Bernie Sanders led to the approval of …
News
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Eisai releases new Phase 2 data for levatinib+everolimus combo in advanced kidney cancer

February 17, 2020 Research and Development, Sales and Marketing Cancer, Eisai, Kidney cancer, Lenvima, pharma, renal cell carcinoma

New Phase 2 data has been revealed for Eisai’s Lenvima (levatinib), delivered alongside Novartis’ everolimus, for the treatment of unresectable …
News
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Strong Phase 3 data for Takeda’s subcutaneous Entyvio in moderate to severe Crohn’s disease

February 17, 2020 Research and Development, Sales and Marketing Crohn’s disease, Entyvio, Takeda, crohn's disease, pharma

Takeda has shared positive new Phase 3 data on a subcutaneous formulation of its gut-selective biologic Entyvio (vedolizumab) as a …
News
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Experts call on NICE to recommended a ban on OTC codeine sales

February 17, 2020 Research and Development, Sales and Marketing Codein, NICE, opioid crisis, opioids, prescription drugs

Experts have called for a ban on the sale of over the counter codeine as NICE is set to publish …
News
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Top Ten most popular articles on Pharmafile.com this week

February 14, 2020 Business Services, Manufacturing and Production, Medical Communications, Research and Development, Sales and Marketing China, Chinese Coronavirus, Wuhan, Wuhan Coronavirus, china coronavirus, coronavirus

The coronavirus continues to dominate the news, with the disease finally getting treated. In America, a patient has been successfully …
News
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Mumps cases in England rocket four-fold to highest point in a decade

February 14, 2020 Medical Communications, Research and Development MMR vaccine, Vaccine, anti-vaccine, pharma

The incidence of mumps in the England has reached its highest level in 10 years, prompting warnings from health officials …
News
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Eisai withdraws weight loss drug Belviq after FDA highlights cancer risk

February 14, 2020 Medical Communications, Research and Development, Sales and Marketing Belviq, Eisai, FDA, pharma

The FDA has requested that Eisai withdraw its weight loss drug Belviq (lorcaserin) and Belviq XR from the US market …
News
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How do the Presidential frontrunners plan to combat the opioid crisis?

February 12, 2020 Business Services, Manufacturing and Production, Medical Communications, Research and Development, Sales and Marketing 2020 Election, Bernie, Bernie Sanders, Donald Trump, Joe, Joe Biden, Trump

The widespread addiction to extremely potent, legal painkillers has decimated the lives of millions across the United States. Overdoses from …
Feature
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ICR identifies key “microRNA” gene driving chemotherapy resistance in cancer

February 12, 2020 Research and Development Cancer, ICR, pharma

Researchers at the Institute of Cancer Research have discovered that a small RNA molecule known as microRNA gene MIR1249 contributes …
News
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Type 2 diabetes drug Rosiglitazone increases risk of heart problems

February 12, 2020 Research and Development British Medical Journal, diabetes, heart failure, insulin, type 2, type 2 diabetes

A new study has given further evidence that rosiglitazone can contribute to risk of heart problems and heart failure. The …
News
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New report finds that health inequality in the UK greater than previously thought

February 12, 2020 Research and Development NHS, NICE, type 2 diabetes

Men are living seven years in poor health while women are living nearly ten years, according to a new report. …
News
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