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Chlamydia vaccine proves safe in Phase 1 trial

August 13, 2019
Manufacturing and Production chlamydia, clinicla trials, infectious diseases, pharma, vaccines

A chlamydia vaccine has shown to be safe in a Phase 1 clinical trial, according to a study published in …

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Ebola drugs prove 90% effective in clinical trial in DRC

August 13, 2019
Manufacturing and Production, Research and Development Congo, DRC, Ebola, clinical trials, infectious diseases, niaid, pharma

Health professionals in the Democratic Republic of Congo (DRC) are now offering two experimental drugs to people infected with Ebola, …

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Scotland turns down Vertex’s Orkambi

August 13, 2019
Manufacturing and Production Orkambi, SMC, Scotland, Vertex, cystic fibrosis, pharma

The Scottish Medicines Consortium (SMC) has turned down Vertex’ cystic fibrosis drug Orkambi on the grounds that it is not …

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Brammer Bio to set up new plant in Norton, Massachusetts

August 12, 2019
Sales and Marketing Brammer Bio, Massachusetts, US, norton, pharma

Cambridge, Massachusetts-based Brammer Bio is planning to set up a new manufacturing facility in Norton, Massachusetts. The Thermo Fisher subsidiary …

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FDA-approved drug could be used to treat Ebola, study shows

August 12, 2019
Sales and Marketing Ebolas, FDA, Romark, nitazoxanide, pharma, virus

The FDA-approved anti-parasitic drug nitazoxanide could be used as a treatment for Ebola, according to researchers from the Boston Children’s …

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EU unprepared for no-deal Brexit, health experts warn

August 12, 2019
Sales and Marketing EU, Euroepan Union, UK, brexit, pharma

European health experts have warned that a no-deal Brexit could worsen medicines shortages in the European Union. Speaking to Reuters, …

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Senators call on FDA to use “forceful response” against Novartis over faulty data scandal

August 12, 2019
Sales and Marketing AveXis, Bernie Sanders, Elizabeth Warren, FDA, Novartis, Zolgensma

Five senators, including presidential candidates Bernie Sanders and Elizabeth Warren, have condemned Novartis for using “falsified data… to obtain approval …

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Court sides with Amgen in Sandoz’ challenge over patent on Enbrel

August 12, 2019
Sales and Marketing Enbrel, IP, Novartis Amgen, court, patent, pharma

A US court has sided with Amgen in a legal battle over the patent on blockbuster rheumatoid arthritis drug Enbrel. …

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Top Ten most popular articles on Pharmafile.com this week!

August 9, 2019
Business Services, Manufacturing and Production, Medical Communications, Research and Development, Sales and Marketing AI, CAR T, CAR-T, Eli Lilly, Lexicon, Medicare, Novartis, Pfizer, Sanofi, pharma

This week’s top story covered the scandal surrounding Novartis over its covering up of faulty data from the FDA. The …

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MS drug boosts effectiveness of cancer therapy in treating glioblastoma, study shows

August 9, 2019
Medical Communications MS, brain cancer, glioblastoma, oncology, pharma

The multiple sclerosis (MS) drug teriflunomide boosts the effectiveness of cancer drugs in treating glioblastoma, according to researchers from UC, …

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Scientists use duoCAR-T therapy to fight HIV

August 9, 2019
Medical Communications AIDS, CAR-T therapy, HIV, health, immunotherapy, pharma

Researchers from the University of Pittsburgh, working with the biotech Lentigen, have found that an advanced form of CAR-T therapy …

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AstraZeneca’s Tagrisso improves overall survival in lung cancer in Phase 3 trial

August 9, 2019
Medical Communications AstraZeneca, Cancer, Tagrisso, lung cancer, oncology, pharma

AstraZeneca has said its cancer drug Tagrisso significantly improved overall survival in a Phase 3 study of patients with lung …

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Bayer buys BlueRock Therapeutics for $600 million

August 9, 2019
Medical Communications Bayer, BlueRock, acquisitions, cell therapies, pharma

Bayer has entered into an agreement to fully acquire engineered cell therapy firm BlueRock Therapeutics in a deal worth $600 …

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Transgene terminates oncolytic IO combo trial in advanced liver cancer

August 8, 2019
Research and Development Cancer, Transgene, clinical trials, liver cancer, pharma

Biotech firm Transgene has announced its decision to terminate a study investigating the efficacy of its oncolytic immunotherapy product Pexa-Vec …

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Medicare will cover CAR-T therapies in United States

August 8, 2019
Sales and Marketing CAR-T therapies, Cancer, Gilead, Kymriah, Medicare, Novartis, keytruda, pharma

Medicare will cover the cost of Novartis’ and Gilead’s CAR-T therapies Kymriah and Yescarta, the US Centers for Medicare and …

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Keytruda/chemo combo recommended for first-line lung cancer via Cancer Drugs Fund

August 8, 2019
Sales and Marketing CDF, Cancer, MSD, NHS, NICE, UK, keytruda, lung cancer, pharma

MSD’s Keytruda (pembrolizumab) has secured recommendation from NICE for inclusion on the Cancer Drugs Fund (CDF) in combination with chemotherapy …

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Gilead’s PrEP drug Descovy should be approved for men and transgender women but not cis-gender women, FDA advisory panel says

August 8, 2019
Research and Development AIDS, Gilead, HIV, PrEP, descovy, pharma

Independent experts on a panel advising the FDA have voted in favour of Gilead’s new PrEP drug Descovy in men …

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Rhythm Pharma’s obesity drug shows positive results in two Phase 3 trials

August 8, 2019
Research and Development Rhythm pharma, clinical trial, health, obesity, pharma

Rhythm Pharma’s obesity drug setmelanotide achieved positive results in two pivotal Phase 3 trials. In both studies, setmelanotide met its …

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Sanofi’s Dupixent improves skin clearance in paediatric atopic dermatitis

August 7, 2019
Research and Development Dupixent, Sanofi, atopic dermatitis, pharma

As the therapy secured approval in Europe for treatment of adolescent patients with moderate-to-severe atopic dermatitis, Sanofi has revealed new …

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AstraZeneca’s Lynparza meets primary endpoint in Phase 3 prostate cancer trial

August 7, 2019
Research and Development Lynpraza, PARP inhibitor, lynparza, pharma, prostate cancer

AstraZeneca’s PARP inhibitor Lynparza was successful in improving progression free survival in a Phase 3 trial of patients with metastatic …

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