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Research and Development

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Higher mutational burdens in tumours linked to greater immunotherapy success, study finds

December 21, 2017 Research and Development Cancer, Johns Hopkins Kimmel Cancer Center, checkpoint inhibitors, mutational burden, pharma

New research from the Johns Hopkins Kimmel Cancer Center and its Bloomberg-Kimmel Cancer Institute for Cancer Immunotherapy has indicated that …
News
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The rare disease climate in Europe

December 21, 2017 Business Services, Manufacturing and Production, Medical Communications, Research and Development, Sales and Marketing biotech, drugs, pharma, pharmaceutical, rare disease

Continuing on from this week’s earlier feature on the rare disease situation in the US, Pharmafile moves its attention onto …
Feature
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Death in trial blackens AbbVie’s positive rheumatoid arthritis data

December 21, 2017 Research and Development AbbVie, biotech, drugs, pharma, pharmaceutical, rheumatoid arthritis

AbbVie posted strong results from its Phase 3 trial into its treatment for rheumatoid arthritis, upadacitinib, but discussions of the …
News

J&J struck by €25m fine over fentanyl pain patch

December 20, 2017 Research and Development, Sales and Marketing Johnson & Johnson, biotech, drugs, fentanyl, pharma, pharmaceutical

Johnson & Johnson has been fined by France’s competition authority, Autorité de la Concurrence, after it alleges the company had …
News
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Genentech seals deal with DiCE Molecules

December 20, 2017 Research and Development, Sales and Marketing DiCE, Genentech, Sanofi, biotech, drugs, pharma, pharmaceutical

Genentech has followed in the footsteps of its parent company by signing a drug discovery agreement with DiCE Molecules. The …
News

NICE recommends Novartis’ Extavia for MS, but knocks back a raft of other beta interferons

December 20, 2017 Research and Development, Sales and Marketing Extavia, MS, NICE, Novartis, beta interferon, multiple sclerosis

NICE has revealed that it has passed draft guidance that recommends Novartis’ Extavia (interferon beta 1b) for the treatment of …
News
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GSK forced to pay back £1.5m to Scottish Government after recent job cuts

December 20, 2017 Manufacturing and Production, Research and Development GSK, GlaxoSmithKline, pharma

British pharmaceutical giant GlaxoSmithKline has been ordered to pay back £1.5 million to the Scottish Government because of its failure …
News

Spark gains approval for gene therapy, paving way for first $1m treatment

December 20, 2017 Research and Development, Sales and Marketing Spark Therapeutics, biotech, drugs, gene therapy, pharma, pharmaceutical

The FDA handed approval to Spark Therapeutics’ gene therapy for an inherited eye disorder, making it the first treatment of …
News
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Allergan and Gedeon Richter’s Vraylar posts strong Phase 3 data in bipolar depression

December 19, 2017 Manufacturing and Production, Research and Development Allergan, Gedeon Richter, Vraylar, bipolar, bipolar depression, pharma

Vraylar (cariprazine), a drug developed as part of a partnership between Allergan and Gedeon Richter, has demonstrated strong results at …
News
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Rare disease medicines access faces a perfect storm

December 18, 2017 Business Services, Manufacturing and Production, Medical Communications, Research and Development, Sales and Marketing biotech, drugs, pharma, pharmaceutical, rare disease

With access to rare disease treatments coming under increasing attention, both in the EU and the US, Pharmafile.com took the …
Feature
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Keytruda falls hard at gastric cancer hurdle

December 18, 2017 Research and Development, Sales and Marketing MSD, biotech, drugs, keytruda, pharma, pharmaceutical

There was a time when PD-1/L1 immunotherapy treatments could do no wrong, blasting through indication after indication. However, the limits …
News
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Cancer Research UK agrees largest drug discovery collab to date

December 15, 2017 Medical Communications, Research and Development Cancer Research UK, Celgene, biotech, drugs, pharma, pharmaceutical

Cancer Research UK has announced that its subsidiary, Cancer Research Technology (CRT), and Celgene have agreed a drug discovery collaboration. …
News
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Top Ten most popular articles on Pharmafile.com this week

December 15, 2017 Business Services, Manufacturing and Production, Medical Communications, Research and Development, Sales and Marketing Ionis, Sanofi, Teva, haemophilia, pharma, top ten

Just 10 days away from Christmas, and big news is still flowing in the industry. Sanofi remains embroiled in scandal …
News
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Working Life: Dr Rav Seeruthun, Medical Director of Roche UK

December 14, 2017 Business Services, Manufacturing and Production, Medical Communications, Research and Development, Sales and Marketing Roche, biotech, drugs, pharma, pharmaceutical

Pharmafile.com sat down with Dr Rav Seeruthun, Medical Director of Roche UK, to discuss his career thus far and the lessons …
Feature
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‘Mind-blowing’ gene therapy could herald a cure for haemophilia, study shows

December 14, 2017 Research and Development haemophilia, pharma

A team of clinical researchers at Barts Health NHS Trust and Queen Mary University of London have reported that a …
News
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