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Common antidepressants linked to dementia risk

April 26, 2018
Medical Communications anticholinergic, biotech, dementia, drugs, pharma, pharmaceutical

A large study looking at the public’s use of anticholinergic drugs, such as those used to treat depression and Parkinson’s, …

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Lilly’s arthritis drug found to prevent potentially lethal stem cell transplant complications

April 25, 2018
Research and Development Cancer, Eli Lilly, JAK inhibitors, Stem cells, baricitinib, graft-versus-host disease, pharma

Researchers at St Louis Washington University School of Medicine have uncovered a promising extra application of a particular Janus Kinase …

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Juno CEO and Co-founder steps down in wake of Celgene acquisition

April 25, 2018
Medical Communications, Research and Development Celgene, appointment, juno therapeutics, pharma

Hans Bishop, CEO and Co-founder of Juno Therapeutics who helped set up the company in 2013 and has since grown …

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Novartis forges forward into digital pharma with FocalView app

April 25, 2018
Medical Communications, Research and Development FocalView, Novartis, biotech, drugs, pharma, pharmaceutical

There is a growing trend in big pharma to talk up the potential for digital technology to revolutionise operations and …

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Sanofi makes ex-Roche scientist new R&D chief

April 25, 2018
Medical Communications, Research and Development Roche, Sanofi, biotech, drugs, pharma, pharmaceutical

With the retirement of Elias Zerhouni as Head of Global R&D, Sanofi had to find a suitable replacement and believes …

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$64bn Takeda-Shire mega merger inches closer to closing

April 25, 2018
Research and Development, Sales and Marketing Shire, Takeda, biotech, drugs, pharma, pharmaceutical

From March onwards, Takeda has been nudging a deal with Shire onwards through repeatedly improved offers, which has seen the …

MHRA bans sodium valproate in the UK following birth defect controversy

April 24, 2018
Manufacturing and Production, Research and Development, Sales and Marketing MHRA, Sanofi, Sodium valproate, bipolar, epilepsy, pharma

The UK Medicines and Healthcare products Regulatory Agency (MHRA) has announced that sodium valproate, a drug used in the treatment …

Lilly’s arthritis drug hits trouble at FDA committee

April 24, 2018
Manufacturing and Production, Sales and Marketing Eli Lilly, Incyte, biotech, drugs, pharma, pharmaceutical, rheumatoid arthritis

FDA’s advisory committee were openly conflicted about deciding on the safety of Eli Lilly and Incyte’s drug, baricitinib, for the …

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AZ’s combo woes continue, with failure in lung cancer

April 24, 2018
Manufacturing and Production, Research and Development AstraZeneca, Imfinzi, biotech, drugs, pharma, pharmaceutical

AstraZeneca has been hit by a fresh blow in its search for an immunotherapy combination treatment that could differentiate it …

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Prothena collapses on double trial failure

April 23, 2018
Manufacturing and Production, Research and Development Prothena Therapeutics, biotech, drugs, pharma, pharmaceutical

Shares in Prothena have dropped by close to 70% on the news that two of its trials into its lead …

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Living with atrial fibrillation

April 23, 2018
Business Services, Manufacturing and Production, Medical Communications, Research and Development, Sales and Marketing KardiaMobile, Tony Green, atrial fibrillation, patient experience

Tony Green discusses the difficulty in pinning down his diagnosis of the irregular heart rhythm condition, until his use of …

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Novartis expands Pear partnership to tackle opioid and substance use disorder

April 23, 2018
Research and Development, Sales and Marketing Novartis, Pear Therapeutics, Sandoz, opioids, pharma, substance use disorder

Novartis has announced that it will expand its current partnership with Pear Therapeutics, signed in March, as it reveals that …

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Biogen boosts pipeline with $1bn Ionis deal

April 23, 2018
Sales and Marketing Biogen, Ionis, Spinraza, biotech, drugs, pharma, pharmaceutical

Somewhat unusually for an early drug development deal, Biogen has put down a serious amount of cash up-front in its …

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CHMP rejects AB Science’s ALS therapy in Europe

April 23, 2018
Sales and Marketing AB Sciences, EMA, European Medicines Agency, ab science, als, masitinib, pharma

AB Science has revealed that the European Medicines Agency’s Committee for Medicinal Products for Human Use (CHMP) has adopted a …

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Fresenius attempts to back out of $4.75bn deal for Akorn

April 23, 2018
Sales and Marketing

Fresenius has announced its intention to terminate the merger agreement with Akorn, over the $4.75 billion deal that the two …

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UK Ministers call on Vertex to speed up price negotiations

April 23, 2018
Sales and Marketing NHS, NICE, Orkambi, UK government, Vertex, biotech, drugs, pharma, pharmaceutical

After a parliamentary debate in the House of Commons regarding making Orkambi available to patients with cystic fibrosis (CF), MPs …

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Top Ten most popular articles on Pharmafile.com this week

April 20, 2018
Business Services, Manufacturing and Production, Medical Communications, Research and Development, Sales and Marketing Amgen, EMA, GW Pharma, J&J, JJ, MHRA, Mylan, Novartis, Sanofi, Shire, Takeda, biotech, drugs, epipen, keytruda, pharma, pharmaceutical

It’s the end of another week and there’s really been one story that has dominated the headlines – Takeda’s potential …

Lilly and Incyte’s resubmission of arthritis drug data fails to assuage FDA concerns

April 20, 2018
Medical Communications, Sales and Marketing Eli Lilly, FDA, Incyte, baricitinib, pharma, rheumatoid arthritis

Eli Lilly and Incyte are facing more complications in the US approval of their experimental rheumatoid arthritis (RA) drug baricitinib …

Prototype skin implant signals cancer by forming a visible mole

April 20, 2018
Medical Communications Cancer, device, implant, medtech, pharma

Researchers working with Professor Martin Fussenegger at the Department of Biosystems Science and Engineering at ETH Zurich in Basel have …

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