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Very high concentrations of pharmaceuticals found in animals in Australian streams

November 7, 2018
Research and Development Contamination, ecosystems, environment, pharmaceuticals, pollution

More than 60 different pharmaceutical compounds were detected in aquatic invertebrate larvae and riparian predators in six streams near Melbourne, …

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UK to push earlier diagnosis and better treatment with 5 AI-driven technology centres

November 6, 2018
Manufacturing and Production, Research and Development AI, Leeds, London, Oxford, UK, glasgow, pharma

The UK’s Business Secretary has announced the introduction of five specialist collaborative centres across the UK which with leverage advanced …

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Clearside Biomedical shares plummet by 56% after disappointing Phase 3 results

November 6, 2018
Manufacturing and Production

Shares in the US-based pharma firm Clearside Biomedical plummeted on Monday after the company announced disappointing phase III trial results …

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Health Secretary launches new prevention strategy for NHS

November 6, 2018
Manufacturing and Production Matt Hancock, NHS, health, prevention

British Health Secretary Matt Hancock has said that healthcare should focus on prevention, as he launched a long-term strategy intended …

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AstraZeneca sells off three drugs in deal worth $350 million

November 6, 2018
Manufacturing and Production AstraZeneca, asthma, covis, deal, royalties

Anglo-Swedish multinational AstraZeneca has agreed to sell the rights to three asthma and rhinitis drugs in a deal worth $350 …

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J&J buy global rights to Yuhan’s lazertinib in deal worth $1.2bn

November 6, 2018
Manufacturing and Production J&J, JJ, NSCLC, Yuhan, deal, lazertinib, south korea

Johnson & Johnson’s Janssen Biotech unit has bought the rights to Yuhan’s third-generation EGFR tyrosine kinase inhibitor (TKI) lazertinib in a deal …

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The November 2018 issue of Pharmafocus is available to read online now!

November 6, 2018
Business Services, Manufacturing and Production, Medical Communications, Research and Development, Sales and Marketing EU, President trump, Trump, anti vaxxer, brexit, clinical trials, opioid crisis, opioids, pharma, vaccines

As the US continues to battle the demons in its healthcare system, Donald Trump looks like he may finally make …

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Anti-vaxxers: Vaccines in the age of populism

November 6, 2018
Business Services, Manufacturing and Production, Medical Communications, Research and Development, Sales and Marketing anti vaccine, anti-vaccine, history, medicine, populism, vaccines

Mistrust of the establishment has fuelled anti-vaccine sentiment in recent years, and adherence has waned as a result. Louis Goss …

Feature

FDA controversially approves potent opioid up to ten times stronger than fentanyl

November 6, 2018
Sales and Marketing Dsuvia, FDA, US, fentanyl, opioid crisis, opioids, pharma

Despite voices of criticism, the FDA has opted to approve AcelRX’s Dsuvia (sufentanil), an opioid medication said to be five …

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Aurobindo pharma initiate recall of blood pressure drug Ibesartan

November 6, 2018
Manufacturing and Production, Research and Development Aurobindo Pharma, FDA, heart drug, ibesartan, recall

Indian pharma firm Aurobindo Pharma Ltd has initiated a voluntary recall of 22 batches of blood pressure drug Ibesartan, due …

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76% of patients no longer experience PTSD a year after MDMA-assisted psychotherapy

November 6, 2018
Manufacturing and Production, Research and Development MDMA, PTSD, mental health, psychotherapy, research

Promising phase II results suggest that MDMA-assisted psychotherapy may be an “innovative, efficacious treatment for posttraumatic stress disorder,” according to …

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HIV drug reduces viral load by 99% within 4 weeks

November 6, 2018
Manufacturing and Production, Research and Development

HIV-drug Gammora may eliminate 99% of the HIV virus within four weeks of treatment, according to the results of a …

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GSK’s anti-seizure drug shows promise in early depression study

November 2, 2018
Medical Communications, Research and Development GSK, GlaxoSmithKline, Potiga, depression, pharma

Researchers have found that GlaxoSmithKline’s ezogabine (Potiga), approved by the FDA in 2011 as an anti-seizure therapy, could have applications …

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Top Ten most popular articles on Pharmafile.com this week!

November 2, 2018
Business Services, Manufacturing and Production, Medical Communications, Research and Development, Sales and Marketing AstraZeneca, GSK, ITH Pharma, J&J, JJ, NICE, Sanofi, Trump, top 10

Deals dominated the headlines this week as both Sanofi and AstraZeneca made billion dollar agreements. Meanwhile, the FDA gave magic …

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Committee advises against FDA approval of Alkermes’ novel depression drug

November 2, 2018
Medical Communications, Sales and Marketing Alkermes, FDA, depression, pharma

Alkermes has been knocked back with the disappointing, though not entirely unexpected, news that the FDA-appointed Psychopharmacologic Drugs Advisory Committee …

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Novo Nordisk cuts 1300 jobs in the midst of Trump’s pricing pressures and depreciation of US dollar

November 2, 2018
Medical Communications Jobs, Novo Nordisk, Trump, pressure, pricing, revenue

Danish multinational Novo Nordisk has said that they will have cut 1,300 employees by the end of 2018. The decision …

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GW Pharma’s Epidiolex becomes first cannabis-based medicine to be made available in United States

November 2, 2018
Medical Communications Epidiolex, GW Pharma, Medical marijuana, cannabidiol, cannabis

GW Pharma’s Epidiolex has become the first plant-derived, cannabis-based medicine to be made available on prescription in all 50 US …

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Galectin-3: The protein paving new treatment avenues

November 1, 2018
Business Services, Manufacturing and Production, Medical Communications, Research and Development, Sales and Marketing Galectin-3, Galectins, breast cancer, diabetes, heart disease, pharma

Matthew Blakeley, LADI-III Beamline Scientist at Institut Laue-Langevin (ILL) and Derek Logan, Associate Professor in Structural Biology at Lund University, …

Feature

Sanofi teams up with Denali in $1.125bn neurological and inflammatory development deal

November 1, 2018
Research and Development, Sales and Marketing Denali Therapeutics, Sanofi, pharma

Sanofi has sealed the deal with Denali Therapeutics to leverage the latter’s small molecule candidates in the development of new …

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Medical Marijuana to be legalised in Thailand and Malaysia as drug becomes available on prescription in UK

November 1, 2018
Business Services, Medical Communications Medical marijuana, UK, cannabis, malaysia, thailand

Thailand’s public health ministry is working to make medical marijuana legal by next month. The shift is expected to come …

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