Research and Development

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Amgen and AstraZeneca’s experimental drug cuts asthma exacerbations by up to 71%

September 7, 2017 Research and Development Amgen, AstraZeneca, MedImmune, asthma, pharma, pharmaceutical, tezepelumab

An anti-TSLP monoclonal antibody jointly developed by Amgen and AstraZeneca’s global biologics and research division, MedImmune, has met its primary …
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AstraZeneca’s Brilinta protects against adverse cardiovascular events for up to 5 years, new data reveals

September 7, 2017 Research and Development AstraZeneca, Brilinta, cardiovascular, heart attack, pharma, pharmaceutical, ticagrelor, trial

AstraZeneca has revealed new data supporting the long-term use and efficacy of its cardiovascular drug Brilinta (ticagrelor), showing that the …

FDA halts trial after first CAR T-associated patient death

September 6, 2017 Research and Development CAR T, CAR-T, Cancer, FDA, cellectis, leukaemia, patient death, pharma, pharmaceutical

French clinical-stage biopharma firm Cellectis has received an order from the FDA to halt its study of CAR T therapy …
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Novo Nordisk settles lawsuit over illegal marketing practices for $58.7 million

September 6, 2017 Research and Development, Sales and Marketing FDA, Novo Nordisk, US, US Justice Department, Victoza, diabetes, pharma, pharmaceutical

Novo Nordisk has resolved a probe by the US Justice Department which accused the Danish drugmaker of illegal marketing activities …

Anti-HIV drug PrEP proves safety in gay and bisexual adolescents

September 6, 2017 Research and Development Gilead, HIV, Pharamceuticals, PrEP, Truvada, health, medicine, pharma

A new study has found that pre-exposure prophylaxis (PrEP) drugs such as Gilead’s Truvada (emtricitabine/tenofovir disoproxil fumarate), which pre-emptively protects …
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Real-world data prove efficacy of Eisai and Bial’s epilepsy treatment

September 6, 2017 Research and Development Bial, Eisai, Zebinix, epilepsy, pharma

Bial and Eisai have released real-world data which support the efficacy of Zebinix (eslicarbazepine acetate) in the treatment of partial-onset …
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Novartis exec designated as new CEO after Jimenez announces retirement

September 5, 2017 Business Services, Manufacturing and Production, Medical Communications, Research and Development, Sales and Marketing CEO, Novartis, a, joe jimenez, phar, pharma, pharmaceuticals

Novartis has announced that its Chief Executive, Joe Jimenez, is set to retire next year. In his place, Vasant Narasimhan …

Takeda’s Ninlaro knocked back by NICE for second time

September 5, 2017 Research and Development, Sales and Marketing Ninlaro, Takeda, biotech, drugs, pharma, pharmaceutical

NICE has revealed that the outcome of its consultation process for Ninlaro (ixazomib), Takeda’s treatment for relapsed or refractory multiple …
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Novartis celebrates success of Gilenya in paediatric multiple sclerosis

September 5, 2017 Manufacturing and Production, Research and Development MS, Novartis, gilenya, health, multiple sclerosis, pharma, pharmaceuticals

Novartis has announced results of its Phase 3 study investigating the safety and efficacy of Gilenya (fingolimod) , finding that …
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Asthma drugs reduce Parkinson’s risk by 50%, decade-long study finds

September 5, 2017 Manufacturing and Production, Research and Development Parkinson's, Parkinson's disease, asthma, pharma, pharmaceuticals, salbutamol

A study from the Department of Global Public Health and Primary Care at the University of Bergen (UiB) in Norway …
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Takeda partners up to develop “next generation” CAR T solid tumour therapy

September 4, 2017 Research and Development, Sales and Marketing CAR T, CAR-T, Cancer, Noile-Immune, Takeda, pharma, pharmaceuticals

Takeda is set to partner with Noile-Immune Biotech in the development of a “next generation” chimeric antigen receptor T-cell (CAR …

Sanofi backs out of controversial Zika vaccine project

September 4, 2017 Research and Development, Sales and Marketing Sanofi, US, Vaccine, Zika, biotech, drugs, pharma, pharmaceutical

Sanofi’s development of a Zika vaccine, alongside the US’s Biomedical Advanced Research and Development Authority (BARDA), has hit the headlines …
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Top Ten most popular articles on Pharmafile.com this week

September 1, 2017 Business Services, Manufacturing and Production, Medical Communications, Research and Development, Sales and Marketing Cancer, Trump, drugs, health, life sciences, medicine, pharma, pharmaceutical, top ten

This week saw the news of a breakthrough in bispecific antibody production and Merck KGaA finally secured approval for its …
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