Research and Development

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Janssen chalks up two more indications in Europe for Imbruvica combo therapies

August 14, 2019 Research and Development, Sales and Marketing Europe, Janssen, chronic lymphocytic leukaemia, imbruvica, pharma

Janssen’s has secured a label expansion from the European Commission for its Bruton’s tyrosine kinase (BTK) inhibitor Imbruvica (ibrutinib), approving …

Aspen Pharmacare to pay £8 million after colluding to rip off NHS

August 14, 2019 Research and Development Addison's disease, Aspen Pharmacare, CMA, NHS, pharma

South African firm Aspen Pharmacare has agreed to pay £8 million to Britain’s NHS over a dispute about overpayment. The …
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Living in polluted city for ten years increases risk of lung disease as much as pack of cigarettes a day for 29 years

August 14, 2019 Research and Development Air pollution, COPD, lung disease, pharma emphysema, public health

Air pollution in cities dramatically increases the risk for and risk of progression of emphysema, a form of chronic obstructive …
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Senate Finance Comittee Chairman, Chuck Grassley calls on Novartis to reveal details of data scandal

August 13, 2019 Research and Development AveXis, Chuck Grassley, Novartis, Zolgensma, sfc

Chuck Grassley, Chairman of the Senate Finance Committee, has demanded that Novartis give up details on the faulty data scandal …
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Making things personal: Roche and personalised medicine

August 13, 2019 Business Services, Manufacturing and Production, Medical Communications, Research and Development, Sales and Marketing Roche, feature, personalised medicine, pharma

Ann Costello, Global Franchise Lead, Centralised Solutions at Roche Diagnostics, discusses the increasing need for a personalised approach to patient …
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MSD teams up with Harvard University to discover novel immune system pathways to fight cancer

August 13, 2019 Manufacturing and Production, Research and Development Cancer, Harvard, MSD, Merck, immuno-oncology, oncology, pharma

A new partnership between MSD and Harvard University hopes to combine the expertise of both parties to carve a path …
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Ebola drugs prove 90% effective in clinical trial in DRC

August 13, 2019 Manufacturing and Production, Research and Development Congo, DRC, Ebola, clinical trials, infectious diseases, niaid, pharma

Health professionals in the Democratic Republic of Congo (DRC) are now offering two experimental drugs to people infected with Ebola, …
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Top Ten most popular articles on Pharmafile.com this week!

August 9, 2019 Business Services, Manufacturing and Production, Medical Communications, Research and Development, Sales and Marketing AI, CAR T, CAR-T, Eli Lilly, Lexicon, Medicare, Novartis, Pfizer, Sanofi, pharma

This week’s top story covered the scandal surrounding Novartis over its covering up of faulty data from the FDA. The …
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Transgene terminates oncolytic IO combo trial in advanced liver cancer

August 8, 2019 Research and Development Cancer, Transgene, clinical trials, liver cancer, pharma

Biotech firm Transgene has announced its decision to terminate a study investigating the efficacy of its oncolytic immunotherapy product Pexa-Vec …
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Gilead’s PrEP drug Descovy should be approved for men and transgender women but not cis-gender women, FDA advisory panel says

August 8, 2019 Research and Development AIDS, Gilead, HIV, PrEP, descovy, pharma

Independent experts on a panel advising the FDA have voted in favour of Gilead’s new PrEP drug Descovy in men …

Rhythm Pharma’s obesity drug shows positive results in two Phase 3 trials

August 8, 2019 Research and Development Rhythm pharma, clinical trial, health, obesity, pharma

Rhythm Pharma’s obesity drug setmelanotide achieved positive results in two pivotal Phase 3 trials. In both studies, setmelanotide met its …
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Sanofi’s Dupixent improves skin clearance in paediatric atopic dermatitis

August 7, 2019 Research and Development Dupixent, Sanofi, atopic dermatitis, pharma

As the therapy secured approval in Europe for treatment of adolescent patients with moderate-to-severe atopic dermatitis, Sanofi has revealed new …
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AstraZeneca’s Lynparza meets primary endpoint in Phase 3 prostate cancer trial

August 7, 2019 Research and Development Lynpraza, PARP inhibitor, lynparza, pharma, prostate cancer

AstraZeneca’s PARP inhibitor Lynparza was successful in improving progression free survival in a Phase 3 trial of patients with metastatic …

NICE recommends Pierre Fabre’s Nerlynx in adjuvant HER2+ breast cancer

August 7, 2019 Research and Development, Sales and Marketing Cancer, NCIE, NHS, Nerlynx, Pierre Fabre, UK, breast cancer

Pierre Fabre’s Nerlynx (neratinib) has been recommended by NICE as a new option for NHS patients with early hormone-receptor-positive, human …
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Medicinal cannabis company Spectrum makes first shipment into UK

August 7, 2019 Research and Development Spectrum, UK, cannabis, medicinalcannabis, pharma

Medicinal cannabis company Spectrum Europe has made its first shipment of cannabis into the UK, making it one of the …
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