Research and Development

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lynparza

Europe approves Lynparza in HER2-, gBRCAm advanced breast cancer

April 10, 2019 Research and Development, Sales and Marketing AstraZeneca, Cancer, MSD, breast cancer, lynparza, pharma

Lynparza (olparib), the poly ADP ribose polymerase (PARP) inhibitor developed by AstraZeneca and MSD, has been awarded marketing approval by …
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New Yorkers must be vaccinated or face a fine

April 10, 2019 Research and Development Brooklyn, New York, infectious diseases, measles, public health, vaccines

A public health emergency has been declared in New York following an outbreak of measles. Residents of certain postcodes in …
senatefloor

Pharmacy Benefit Manager (PBM) execs testify before US Senate

April 10, 2019 Research and Development PBMs, Rebates, Senate, US, pharma, senator, sfc

Executives representing pharmacy benefit managers (PBMs) appeared before the US Senate Finance Committee on Tuesday as they testified on the …
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United Therapeutics terminates oral pulmonary arterial hypertension drug following Phase 3 failure

April 9, 2019 Manufacturing and Production, Research and Development Tyvaso, United Therapeutics, pharma, pulmonary arterial hypertension

United Therapeutics has revealed in a short announcement that, because its pulmonary arterial hypertension (PAH) therapy failed to meet its …

ViiV Healthcares scores first twin-drug FDA approval for untreated HIV-1

April 9, 2019 Manufacturing and Production, Research and Development GSK, HIV, ViiV Healthcare, pharma

ViiV Healthcare, the pharmaceutical firm owned by Shionogi, Pfizer and predominantly GSK, has announced its two-drug HIV regimen Dovato (dolutegravir …
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Kymab announces Merck exec Simon Sturge as new CEO

April 8, 2019 Business Services, Manufacturing and Production, Medical Communications, Research and Development, Sales and Marketing Boehringer Ingelheim, appointment, kymab, pharma

UK-based biotech Kymab has identified Merck KGaA executive Simon Sturge as its new Chief Executive Officer, taking over the reins …

NICE turns down Astellas’ Xtandi in prostate cancer

April 8, 2019 Research and Development, Sales and Marketing Astellas, Cancer, NHS, NICE, UK, pharma, prostate cancer

Astellas’ Xtandi (enzalutamide) has been rejected by UK medicines watchdog NICE for use on the NHS as a therapy for …
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Alnylam and Sanofi close research phase of 2014’s $700m RNAi rare disease partnership

April 8, 2019 Research and Development, Sales and Marketing Alnylam, Genzyme, Sanofi, pharma, rare disease

Alnylam and Sanofi have announced their intention to bring to an end the research and option phase of a $700 …
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Osteoporisis risk in over half of European women over 70, three-quarters not treated, Amgen study finds

April 8, 2019 Research and Development, Sales and Marketing Amgen, Europe, UK, bones, osteoporosis, pharma, real world data, real-world data

A new study from Amgen analysing real-world data has revealed that more than half of European women over 70 years …
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Merrimack shuts down development of investigational cancer drug, staff cuts to follow

April 8, 2019 Research and Development, Sales and Marketing cacner, merrimack, oncology, pharma

Merrimack Pharmaceuticals has taken the decision to terminate development of its antibody-directed nanotherapeutic cancer therapy MM-310 in the treatment of …

Memorial Sloan Kettering Cancer Center officials violated conflict of interest policies

April 5, 2019 Medical Communications, Research and Development Cancer, Memorial Sloan Kettering Cancer Center, oncology, research

Top officials at the Memorial Sloan Kettering Cancer Center repeatedly violated policies on financial conflicts of interest, according to details …
theo_harold

Crescendo Biologics selects current CFO Theodora Harold as new CEO

April 4, 2019 Business Services, Manufacturing and Production, Medical Communications, Research and Development, Sales and Marketing CEO, Cambridge, Crescendo Biologics, Dr Peter Pack, Theo Harold, cfo

Cambridge, UK-based Crescendo Biologics have said current Chief Financial Officer (CFO) Theodora Harold will take over from Dr Peter Pack …
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AstraZeneca’s early-stage Fasenra study smashes primary endpoint in hypereosinophilic syndrome

April 4, 2019 Research and Development AstraZeneca, Fasenra, hypereosinophilic syndrome, pharma

AstraZeneca has revealed new data for Fasenra (benralizumab), demonstrating that patients using the drug can “achieve near-complete depletion of eosinophils …
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