Top Ten most popular articles on this week!

pharmafile | November 23, 2018 | News story | Business Services, Manufacturing and Production, Medical Communications, Research and Development, Sales and Marketing Kymriah, Mundipharma, UK, US, brexit, pharma, politics, top 10 

The appointment of GSK veteran Arnaud Breabout to the position of Senior Vice President and CFO of Mundipharma took the top spot this week. Meanwhile MHRA chief Dr Ian Hudson announced he was stepping down.

Equally as Brexit inched ever closer it was revealed that use of antidepressant had gone up in the month following the referendum. At the same time, the ABPI responded to Theresa May’s new deal.

In the wake of the midterms in the United States, American firm Pfizer asked Senator Cindy Hyde-Smith to refund campaign donations after the Republican joked about ‘public hanging’ in her home state of Mississippi.

Check out this week’s top 10 most popular stories on!

10. Kymriah to be made available in UK for paediatric leukaemia patients via Cancer Drugs Fund

NICE has announced its recommendation that Novartis’ CAR-T cell therapy Kymriah (tisagenlecleucel) be made available in the treatment of relapsed or refractory B-cell acute lymphoblastic leukaemia (ALL) for patients under the age of 25 via the Cancer Drugs Fund.

9. Mylan’s Morgantown plant receives FDA warning letter

Generic drugmaker Mylan has received a warning letter from the FDA over concerns surrounding the firm’s manufacturing plant in West Virginia.

8. AstraZeneca’s Imfinzi immunotherapy combo fails to show benefit in lung cancer

AstraZeneca has revealed that its immunotherapy combo of Imfinzi (durvalumab) and tremelimumab failed to meet its primary endpoint in a recent Phase 3 trial in the treatment of previously untreated patients with Stage IV (metastatic) non-small cell lung cancer (NSCLC).

7. Pfizer ask Senator Cindy Hyde-Smith to refund campaign donation after ‘public hanging’ comments

American pharma giant Pfizer have asked Mississippi Republican Senator Cindy Hyde-Smith to return campaign donations after the candidate was filmed joking about attending a “public hanging”.

6. Brexit referendum led to rise in antidepressant prescriptions

The result of the Brexit referendum led to an increase in prescriptions for antidepressants, according to a study conducted by researchers at King’s College London.

5. Pfizer defeated in Britain’s highest court over Lyrica patent

American pharma firm Pfizer have lost in the final round of a protracted court battle over the patent on epilepsy drug Lyrica, after Britain’s highest court ruled against the company, in a case surrounding the $5 billion a year drug.

4. MHRA Chief to step down in 2019

The Medicines and Healthcare products Regulatory Agency (MHRA), the regulator responsible for the efficacy and safety of medicines in the UK, has announced that its Chief Executive is to step down from the role in September next year.

3. Eli Lilly’s Emgality cleared for treatment of migraine in Europe

Eli Lilly’s Emgality (galcanezumab) has secured approval from the European Commission for the prophylaxis of migraine in adult patients who have at least four days affected by the condition per month, it has emerged.

2. Roche withdraws Tecentriq combo application in first-line renal cell carcinoma

The EMA has revealed that Roche has chosen to withdraw its marketing application for immunotherapy Tecentriq (atezolizumab) in combination with Genentech’s Avastin (bevacizumab) as a first-line treatment for renal cell carcinoma (RCC) due to insufficient data.

1. Mundipharma name GSK veteran as new Senior Vice President & CFO

The Mundipharma network today confirmed the appointment of Arnaud Breabout, to the position of Senior Vice President & Chief Financial Officer.

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