Synthetic, non-intoxicating CBD analogue treats seizures in rats

pharmafile | May 31, 2019 | News story | Medical Communications CBD, H2CBD, cannabidiol, medicinal cannabis, pharma 

A synthetic, non-intoxicating cannabidiol (CBD)-analogue is effective at treating seizures in rats, according to researchers at the University of California, Davis.

The molecule, 8,9-Dihydrocannabidiol (H2CBD) is a synthetic molecule which is structurally similar to the CBD. Mascal’s lab developed H2CBD from commercially available chemicals.

The UC Davis researchers tested H2CBD against CBD, in rats with induced seizures. Both drugs were found to be equally effective in treating seizures in rats.

“It’s a much safer drug than CBD, with no abuse potential and doesn’t require the cultivation of hemp,” said Mark Mascal, professor in the UC Davis Department of Chemistry.

Mascal is now working with colleagues to carry out further clinical trials. The teams findings were published in the journal Scientific Reports.

Louis Goss

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