CDC investigating post-vaccine inflammation reports in the US

pharmafile | May 24, 2021 | News story | Sales and Marketing  

The US Centers for Disease Control (CDC) is looking in to a small number of reports that some young vaccine recipients experienced heart inflammation.

Those who developed myocarditis, an inflammation of the heart muscle, were predominantly adolescents and young adults, and predominantly male.

The condition often goes away without complications and can be caused by a variety of viruses, and it has been recommended for further investigation.

CDC monitoring systems had not found more cases than would be expected in the population, but members of the committee on vaccinations felt that healthcare providers should be made aware of the reports of the “potential adverse event,” the committee said in the statement.

Dr Amesh Adalja, senior scholar at the Johns Hopkins Center for Health Security, said vaccines are known to cause myocarditis and would be important to monitor to see if it is causally related to the vaccine, it is important to look at the risk-benefit ratio.

He said: “Vaccines are going to unequivocally be much more beneficial outweighing this very low, if conclusively established, risk.”

The CDC said the cases typically occurred within four days after receiving the mRNA vaccines. It did not specify which vaccines. The United States has given emergency authorisation to the Moderna and Pfizer-BioNTech vaccines.

Israel’s Health Ministry in April said it was examining a small number of cases of heart inflammation in people who had received the Pfizer vaccine, though it had not yet drawn any conclusions. Most of the cases in Israel were reported among people up to age 30.

Pfizer said at the time it had not observed a higher rate of the condition than would normally be the case in the general population and that a causal link to the vaccine had not been established.

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