failure

Showing 11 posts of 11 posts found.

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AstraZeneca’s selumetinib fails to meet primary endpoint in lung cancer trial again

August 9, 2016
Manufacturing and Production AstraZeneca, failure, non-small cell lung cancer, phase III, selumetinib, trial failure

AstraZeneca has announced that its MEK 1/2 inhibitor, selumetinib, failed to meet its primary endpoint of progression free survival in …

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Chiasma cuts staff by 33% after FDA rejects rare disease drug, Mycapssa

June 16, 2016
Research and Development, Sales and Marketing FDA, chiasma, cutbacks, failure, workforce cuts

US-based biopharmaceutical company, Chiasma (NASDAQ: CHMA), has announced substantial job cuts as it attempts to restructure following the US Food …

Biomarin withdraws regulatory submissions for Duchenne muscular dystrophy drug

June 1, 2016
Research and Development, Sales and Marketing BioMarin, Duchenne Muscular Dystrophy, EMA, FDA, Kyndrisa, failure, rejection

Biomarin (NASDAQ: BMRN) has announced that it has withdrawn its marketing authorisation application for Duchenne muscular dystrophy drug, Kyndrisa (drisapersen), …

Almost 9 in 10 CCGs not implementing NICE guidelines on antibiotic resistance

May 12, 2016
Research and Development, Sales and Marketing CCGs, NICE, antibiotic resistance, failure

The Patients Association has called on all Clinical Commissioning Groups (CCGs) to implement the National Institute for Health and Care …

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Clovis cuts staff by 35% after FDA knock back on lung cancer drug

May 6, 2016
Manufacturing and Production, Research and Development, Sales and Marketing FDA, Q1 results, clovis, failure, job cuts, job losses, rociletinib, workforce

Clovis Oncology (NASDAQ: CLVS) is set to cut up to 35% of its workforce following the US Food and Drug …

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HIV successfully overcomes CRISPR gene-editing technology

April 8, 2016
Research and Development HIV, crispr, failure, setback

Researchers using the CRISPR gene-editing technology have indicated that HIV can defeat efforts to cripple it, but have characterised it …

Novartis heart drug sees stellar results

September 1, 2014
Sales and Marketing Diovan, LCZ696, Novartis, failure, heart, valsartan

Novartis’ new heart pill has produced stellar results in helping patients with heart failure live longer, making it the first …

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Torisel-Avastin combo fails in kidney cancer

August 13, 2012
Research and Development, Sales and Marketing R&D, Sutent, Torisel, avastin, failure, rcc

Combining Pfizer’s Torisel and Roche’s Avastin does not increase survival rates for advanced kidney cancer patients. This is according to …

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Erbitux fails in gastric cancer trial

July 6, 2012
Research and Development, Sales and Marketing Erbitux, Merck Serono, Roche, failure, gastric cancer

Merck’s Erbitux has failed to increase survival in patients with gastric cancer, representing a blow to the firm’s ambition to …

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AstraZeneca pulls depression drug, takes $50m hit

March 20, 2012
Research and Development, Sales and Marketing AstraZeneca, R&D, depression, failure, pipeline

AstraZeneca and partner Targacept will not file their depression drug TC-5214 for regulatory review. The decision comes after disappointing Phase …

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