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Sanofi/GSK COVID-19 vaccine development delayed after failing to induce strong response in over-50s

December 11, 2020 Medical Communications, Research and Development COVID-19, GSK, Sanofi, Vaccine

Sanofi and GlaxoSmithKline have taken the decision to delay the development programme for their adjuvanted recombinant protein-based COVID-19 vaccine after …
News
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Hackers breach EMA server to steal data on Pfizer/BioNTech’s COVID-19 vaccine

December 10, 2020 Research and Development COVID-19, EMA, Vaccine

Pfizer and BioNTech’s jointly-developed COVID-19 vaccine, which this week began to rolled out to elderly patients in the UK after …
News
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UAE reveals 86% effiacy for Sinopharm’s COVID-19 vaccine

December 10, 2020 Research and Development COVID-19, Sinopharm, UAE, Vaccine

The Health Ministry of the United Arab Emirates has unveiled the first known efficacy data for the COVID-19 vaccine candidate …
News
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Lilly’s tirzepatide generates significant reductions in weight and blood sugar in type 2 diabetes patients

December 10, 2020 Research and Development Eli Lilly, diabetes, tirzepatide

Eli Lilly has announced new data for its glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist tirzepatide, showing …
News
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AbbVie unveils new Phase 3 upadacitinib data in moderate to severe ulcerative colitis

December 10, 2020 Research and Development AbbVie, upadacitinib

AbbVie has announced data from the first of two Phase 3 studies investigating the efficacy of upadacitinib in treating moderate …
News
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Pharmafile.com’s weekly COVID-19 news round-up

December 9, 2020 Business Services, Manufacturing and Production, Medical Communications, Research and Development, Sales and Marketing COVID-19, Top 5, pharma

COVID-19 vaccine news continues to roll in and continues to be positive, with AstraZeneca now releasing Phase 3 data that …
News

Novartis’ Kisqali delays need for chemo by over 4 years in post-menopausal HR+HER2- metastatic breast cancer

December 9, 2020 Research and Development Kisqali, Novartis, breast cancer

Novartis has lifted the curtain on updated Phase 3 data for Kisqali (ribociclib) in the treatment of hormone receptor positive, …
News
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MHRA warns patients with history of significant allergic reactions not to receive Pfizer/BioNTech COVID-19 vaccine

December 9, 2020 Research and Development COVID-19, MHRA, UK, Vaccine

While the rolling out of Pfizer and BioNTech’s COVID-19 in the UK this week marked a historic moment in a …
News
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AstraZeneca and Oxford Uni vaccine is safe and effective in preventing COVID-19 infection, Phase 3 data show

December 9, 2020 Research and Development AstraZeneca, COVID-19, Vaccine

The latest efficacy data on the COVID-19 vaccine developed by AstraZeneca in partnership with the University of Oxford have been …
News
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Amryt’s Lojuxta approved in Brazil to reduce cholesterol in homozygous familial hypercholesterolaemia patients

December 9, 2020 Research and Development, Sales and Marketing Amryt, Brazil, rare disease

Brazil’s National Health Surveillance Agency (ANVISA) has moved to authorise Amryt’s Lojuxta (lomitapide) in the country as a treatment for …
News
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Novartis unveils new multi-trial data for CAR-T therapy Kymriah in advanced lymphoma

December 7, 2020 Research and Development, Sales and Marketing CAR-T, Kymriah, Novartis

Novartis has taken the opportunity at the 2020 American Society of Hematology Annual Meeting & Exposition (ASH) to unveil promising …
News
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Jakafi outperforms best available therapy in steroid-refractory/dependent chronic graft-versus-host disease

December 7, 2020 Research and Development, Sales and Marketing Incyte, Jakafi, Novartis

The first Phase 3 findings have been revealed for Jakafi (ruxolitinib) in the treatment of steroid-refractory or steroid-dependent chronic graft-versus-host disease …
News
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Six-year follow-up data shows Imbruvica’s benefit in high-risk chronic lymphocytic leukaemia

December 7, 2020 Research and Development, Sales and Marketing Janssen, chronic lymphocytic leukaemia, imbruvica

Janssen has revealed multiple pooled data analyses for its Bruton’s tyrosine kinase (BTK) inhibitor Imbruvica (ibrutinib) in the first-line treatment …
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Top Ten most popular articles on Pharmafile.com this week

December 4, 2020 Business Services, Manufacturing and Production, Medical Communications, Research and Development, Sales and Marketing COVID-19, Dupixent, EMA, UK, Vaccine, top ten

As the year winds to a close, excitement is rising around the efficacy and availability of COVID-19 vaccines around the …
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New research links metformin to decreased mortality risk in female patients hospitalised with COVID-19

December 4, 2020 Medical Communications, Research and Development COVID-19, Vaccine, metformin

Researchers from the University of Minnesota Medical School (UMMS) and UnitedHealth Group have uncovered potential benefit of metformin, a generic …
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