Research and Development

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Bluebird bio’s Lenti-D gene therapy shows promise in cerebral adrenoleukodystrophy

September 23, 2019 Research and Development, Sales and Marketing Bluebird Bio, cerebral adrenoleukodystrophy, gene therapy, pharma

Bluebird bio has revealed updated data for its investigational Lenti-D gene therapy in the treatment of cerebral adrenoleukodystrophy (CALD), a …
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Antidepressant sertraline works ‘by reducing anxiety symptoms first’

September 20, 2019 Medical Communications, Research and Development antidepressant, sertraline

Researchers at University College London have found that a commonly prescribed antidepressant, sertraline, works in unexpected ways, first relieving users …
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Novo’s Tresiba lowers hypoglycaemia risk compared to insulin glargine in type 2 diabetes

September 20, 2019 Medical Communications, Research and Development Novo Nordisk, Tresiba, diabetes, pharma

Novo Nordisk has unveiled new data for Tresiba (insulin degludec) at the 55th Annual Meeting of the European Association for …
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Biogen to start new Spinraza trial to preserve market share

September 20, 2019 Medical Communications, Research and Development

Biogen is planning a new trial of $1.7billion-a-year Spinraza to investigate much higher doses in spinal muscular atrophy (SMA) and …
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Almost half of all cancer drug trials show bias and exaggeration

September 19, 2019 Research and Development BMJ, Cancer, cancer drug trials

New research on clinical trials between 2014 and 2016 raise “serious concerns about low standards” as over the three year …

Sanofi’s Troujeo beats insulin degludec in head-to-head study in type 2 diabetes

September 19, 2019 Research and Development Sanofi, Troujeo, diabetes, insulin degludec, pharma

Sanofi took the opportunity at the 55th annual European Association for the Study of Diabetes to present new data from …
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British baby’s death not caused by Zolgensma says Novartis

September 19, 2019 Research and Development AveXis, Novartis, Zolgensma, spinal muscular atrophy

Swiss drugmaker Novartis have stated that a British baby’s death this year after getting Novartis’ gene therapy Zolgensma, was not …

NICE recommends Takeda’s Takhzyro for NHS use to prevent hereditary angioedema attacks

September 18, 2019 Research and Development, Sales and Marketing NHS, NICE, Takeda, Takhzyro, pharma

UK drug watchdog NICE has announced its final draft guidance recommending Takeda’s subcutaneous injection Takhzyro (Lanadelumab) for use on the …

US, Canada and Australia simultaneously fast-track Keytruda/Lenvima combo for endometrial cancer

September 18, 2019 Research and Development, Sales and Marketing Australian Therapeutic Goods Administration, Cancer, FDA, Health Canada, Lenvima, keytruda, pharma

The FDA has acted under a new initiative in collaboration with the Australian Therapeutic Goods Administration (TGA) and Health Canada, …

New agreement gives AstraZeneca full responsibility for Linzess in China

September 18, 2019 Research and Development AstraZeneca, IBS-C, Linzess

AstraZeneca has amended its collaboration agreement with Ironwood Pharmaceuticals in China for Linzess (linaclotide), a first-in-class new treatment for patients …
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Swiss biotech raises $16m for ‘undelivery mechanism’ in rare liver disease

September 18, 2019 Research and Development liver disease, versantis

A new method from Swiss Biotech Versantis promises to give far better immediate care and offer a treatment for a …
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Roche bags FDA Breakthrough for Gazyva in lupus nephritis

September 18, 2019 Research and Development FDA, Gazyva, Roche, lupus nephritis

The US FDA has granted Breakthrough Therapy Designation to Gazyva (obinutuzumab) for adults with lupus nephritis. The win comes on …

UKRI Chief Executive Sir Mark Walport to step down in 2020

September 17, 2019 Business Services, Manufacturing and Production, Medical Communications, Research and Development, Sales and Marketing UKRI, appointment, pharma

Sir Mark Walport, Chief Executive of UK Research and Innovation (UKRI), the national funding agency responsible for science and research …
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New experimental approach could stop common cold

September 17, 2019 Manufacturing and Production, Research and Development

Scientists believe they may have found a way to stop the common cold as instead of attacking the virus directly, …
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Acceleron terminates drug candidate following facioscapulohumeral muscular dystrophy failure

September 17, 2019 Manufacturing and Production, Research and Development Acceleron, pharma, trial failure

Acceleron Pharma has seen its stock fall by almost 4% after it unveiled new Phase 2 data confirming that its …
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