Research and Development

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Novartis enters license agreement with Pliant Therapeutics for fibrosis assets

October 24, 2019 Research and Development

Novartis has signed a collaboration and license agreement with Pliant Therapeutics to develop and commercialise preclinical asset PLN-1474 which is …

Novartis receives EC label update approval for Cosentyx in ankylosing spondylitis

October 24, 2019 Research and Development

Novartis has announced that the European Commission has approved a label update for the up-titration of Cosentyx (secukunumab) to 300mg …
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GSK receives wider nod for Zejula as it competes with rival AstraZeneca

October 24, 2019 Research and Development

The US FDA has approved GlaxoSmithKline’s Zejula (niraparib) for the use in advanced ovarian, fallopian tube, or primary peritoneal cancer …
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FDA approves Vertex’s Trikafta in new indication, now potentially covering 90% of cystic fibrosis patients

October 23, 2019 Research and Development, Sales and Marketing FDA, Trikafta, Vertex, cystic fibrosis, pharma

The FDA has granted marketing authorisation to Vertex’s Trikafta (elexacaftor/tezacaftor/ivacaftor and ivacaftor) for the treatment of cystic fibrosis (CF), it …

New study shows Prozac no better than placebo in treating autism

October 23, 2019 Research and Development

A small study has found that the commonly prescribed medication for kids and teenagers with autism is no more effective …
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BMS’ Opdivo+Yervoy+Chemo combo shows superior overall survival in first-line lung cancer

October 23, 2019 Research and Development Bristol-Myers Squibb, Cancer, NSCLC, Yervoy, lung cancer, opdivo, pharma

Bristol Myers Squibb has lifted the curtain on new Phase 3 data for its blockbuster immunotherapy Opdivo (nivolumab), showing that …
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Biogen aiming for Aducanumab to slow Alzheimer’s progression

October 23, 2019 Research and Development

US firm Biogen is hoping for approval to bring about a treatment that could slow the onset of Alzheimer’s disease. …
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Takeda acquires investigational coeliac disease therapy

October 23, 2019 Research and Development

Takeda has acquired licensing for a first-in-class investigational coeliac disease therapy CNP-101/TAK-101. The Japanese pharma giant now has the rights …
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Porton Biopharma signs potential $24m deal to push its intranasal anthrax vaccine into Phase 1 trials

October 22, 2019 Manufacturing and Production, Research and Development FDA, Porton Biopharma, anthrax, pharma

Porton Biopharma has signed a modification to its existing agreement with the US National Institute of Health’s National Institute of …
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“No deal” Brexit and life sciences: What happens?

October 21, 2019 Business Services, Manufacturing and Production, Medical Communications, Research and Development, Sales and Marketing EU, Europe, UK, brexit, no deal, no-deal, pharma

Prime Minister Boris Johnson may have agreed a withdrawal agreement with the European Union at the 11th hour, but despite …
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Roche’s Tecentriq/Avastin combo smashes endpoints at Phase 3 in unresectable hepatocellular carcinoma

October 21, 2019 Research and Development, Sales and Marketing Cancer, Roche, immunotherapy, pharma, tecentriq

New Phase 3 data has emerged demonstrating the efficacy of Roche’s Tecentriq (atezolizumab) in combination with Avastin (bevacizumab) in the …

Medical cannabis: Growth by leaps and bounds

October 18, 2019 Business Services, Manufacturing and Production, Medical Communications, Research and Development, Sales and Marketing Canada, Canopy Growth, medical cannabis, pharma

This article follows parts one and two of our trio of in-depth pieces focusing on the growing medical cannabis phenomenon. …
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Top Ten most popular articles on Pharmafile.com this week

October 18, 2019 Business Services, Manufacturing and Production, Medical Communications, Research and Development, Sales and Marketing

It’s time for a rundown of the top 10 articles on PharmaFile this past week. The past seven days saw …

UCB’s bimekizumab meets primary and secondary endpoints, beating Janssen’s Stelara in chronic plaque psoriasis

October 17, 2019 Research and Development Stelara, UCB Pharma, bimekizumab, pharma, plaque psoriasis

UCB Pharma has announced new data from the first of three Phase 3 studies investigating the efficacy of its IL-17A …
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