The Pharmafile Brief

September 2025 – The Pharmafile Brief

Welcome to the September issue of The Pharmafile Brief, bringing you the latest developments shaping healthcare and pharma this month.

In our third issue, we delve into epilepsy, including rare and severe forms, coinciding with National Epilepsy Awareness Week at the start of September. We also examine changes in access to medicines under the government’s 10-Year Health Plan and highlight the latest advances in AI integration across the industry.

A highlight of this issue is an interview with Amélie Lothe, global medical community head of rare epilepsies at UCB. She discusses developmental and epileptic encephalopathies, providing insight into these lesser-known forms, the treatments currently available, and how she expects the field to evolve.

Amélie Lothe

We continue our new series, The Pharma Files, featuring conversations with leaders across pharma and healthcare who share their perspectives on industry trends, challenges and opportunities. In this issue, we speak with Hatim Abdulhussein, CEO of Health Innovation Kent Surrey Sussex and a practising GP, about the best parts of his job and his proudest moments.

Professor Hatim Abdulhussein

Vision4Health’s founder Sabina Syed discusses the government’s recent Life Sciences Sector Plan and what it could mean for patients. She argues that it signals the UK’s desire to lead, not just in research, but in uptake of health innovation that delivers real-world impact to patients. However, success is contingent on deep understanding, partnership and long-term engagement.

We present the fourth instalment in the Gateway to Local Adoption series, also produced with Visions4Health. Frances Smith, Clinical Pharmacy Services Manager and Cambridge-based pharmacist, shares her views on the government’s 10-Year Health Plan and patient access to medicines. She highlights the creation of a single national formulary and the shift of services from hospital to community as key ways of reshaping access.

Frances Smith

Also in relation to the 10-Year Health Plan, M3, a provider of digital solutions in medical communications, explores how NHS structural changes are as much about marketing as policy. By freeing up pharmacists’ time to treat more patients and expanding their role in frontline care, M3 describes a seismic shift in where healthcare conversations begin.

Our Five Facts for September also focus on epilepsy – from common seizure triggers and high co-morbidity rates to its historical understanding. In addition, the Epilepsy Research Institute has opened its 2025-26 Grant Round, offering funding opportunities to support researchers at all career stages.

With AI integration into healthcare software rapidly underway, this month saw a number of key developments. Cognizant launched TriZetto AI Gateway, embedding generative AI across its healthcare software programmes. Meanwhile, Sanome’s MEMORI – an AI device predicting hospital-acquired infections – became the first UK-built AI software to receive certification for infection prediction.


There were major developments in tackling global health conditions. Sexual health clinics in England began rolling out free vaccines to patients at highest risk of gonorrhoea, aiming to protect thousands. Meanwhile, Eli Lilly’s obesity candidate orforglipron achieved significant weight loss results in a phase 3 trial.


The industry also saw a number of leadership changes. Swedish healthtech company Enzymatica appointed Sana Alajmovic as CEO; radiopharma company Artbio expanded its board and established a technical advisory board; and Richmond Pharmacology promoted Priscilla Ochuba to associate medical director in recognition of her contributions to early-stage research.

We hope you enjoy reading this issue of The Pharmafile Brief. Look out for the next issue in early October, with fresh in-depth analysis across pharma, biotech and healthcare.

Rare and severe epilepsies – current treatments and advance therapeutics

Published on August 29th, 2025

The current forms of immunotherapy, how T cell therapy works and what the future holds
hospital

The Pharma Files: With Professor Hatim Abdulhussein from Health Innovation Kent Surrey Sussex

Published on August 28th, 2025

Pharmafile chats with Priyanka Hinton, Customer Solutions Director at Chase People about the best parts of her job and her proudest moments.

How pharma marketing needs to adapt as community pharmacies take centre stage

Published on August 28th, 2025

The UK government’s 10-Year Health Plan is moving pharmacists to the frontline of primary care For decades, community pharmacies were viewed as the final link in the healthcare chain, the place where prescriptions were filled, questions were answered and patients left with neatly labelled medication in hand. The pharmacist’s role, although respected, was largely reactive:...

The UK’s Life Sciences Sector Plan: a fresh launchpad or a continued labyrinth for the uptake of innovative medicines?

Published on August 27th, 2025

As the UK healthcare system navigates a period of significant change, the path to successful market access is becoming increasingly complex.
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Epilepsy Research Institute opens 2025-26 grant round with new awards

Published on August 21st, 2025

The Epilepsy Research Institute has opened its 2025-26 Grant Round, offering a wide range of funding opportunities designed to support researchers at every stage of their careers. The funding reflects the Institute’s commitment to connecting the epilepsy research community. Applications are invited across all areas of epilepsy research, with new award types introduced this year...

Five Facts about epilepsy

Published on August 21st, 2025

1 Epilepsy occurs when the normal electrical activity in the brain changes. For many, the cause is unclear, but genes and brain damage are understood to be related to the condition.1 2 The risk of premature death in people with epilepsy is up to three times higher than in the general population. A significant portion...

Single national formulary and community care: a closer look at the 10-Year Health Plan

Published on August 21st, 2025

In the fourth of the Gateway to Local Adoption series, Visions4Health caught up with Frances Smith, Clinical Pharmacy Services Manager, Outpatients, to discuss her views on elements of the 10-Year Health Plan for England relating to patient access to medicines.

Enzymatica appoints Sana Alajmovic as new CEO

Published on August 12th, 2025

The board of directors of Enzymatica has appointed Sana Alajmovic as chief executive officer, succeeding Claus Egstrand. Egstrand will step down from his role and will then be nominated to join the company’s board of directors. Alajmovic is currently the co-founder and CEO of Sigrid Therapeutics, a healthtech company specialising in chronic lifestyle diseases. She...

ARTBIO expands board and establishes technical advisory board

Published on August 11th, 2025

ARTBIO, a radiopharma company developing radioligand therapies (RLTs), has appointed four new members to its board of directors and formed a technical advisory board. Firstly, Maha Katabi (pictured top left), a general partner at Sofinnova Investments, with more than 20 years’ experience in biotech leadership and investment, has been appointed. Robert Mittendorff (pictured top right),...
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Lilly reports positive results from trial of obesity candidate

Published on August 8th, 2025

Eli Lilly and Company (Lilly) has announced topline results from its phase 3 ATTAIN-1 trial, showing that orforglipron – a once-daily oral GLP-1 receptor agonist – achieved significant weight loss in adults with obesity or overweight with a related medical condition. Patients receiving the highest dose of orforglipron (36mg) lost an average of 12.4% of...
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Rollout of world-first gonorrhoea vaccine programme begins under NHS

Published on August 8th, 2025

From 4 August, sexual health clinics in England have been able to offer a free vaccine – the 4CMenB vaccine – to patients at highest risk of infection with gonorrhoea. The programme intends to protect thousands from infection risk, and forms part of the UK government’s 10 Year Health Plan, specifically the shift from sickness...
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Sanome’s AI tool gains certification for early detection of hospital infections

Published on August 7th, 2025

Sanome’s MEMORI, an artificial intelligence (AI) medical device that can predict hospital-acquired infections up to 72 hours before they present, has received Class IIb CE certification and approval from the Medicines and Healthcare products Regulatory Agency (MHRA). This marks the first UK-built AI software to receive this level of certification for infection prediction. The tool...
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Cognizant launches tool to support secure AI integration in healthcare platforms

Published on August 7th, 2025

US tech solutions company, Cognizant, has launched TriZetto AI Gateway, a new tool designed to embed generative AI functions across its existing TriZetto healthcare software programmes. The product aims to help health organisations manage AI adoption securely and at scale, particularly in sensitive areas such as claims processing and care management. The product provides a...

Richmond Pharmacology appoints Priscilla Ochuba as associate medical director

Published on August 1st, 2025

Richmond Pharmacology has announced the promotion of Priscilla Ochuba to associate medical director, effective 1 August 2025. The move recognises her outstanding contributions to early-phase research and leadership within the organisation’s medical directorate. Ochuba joined Richmond in 2022 with a background in general medicine and has since become an integral figure in the delivery of...