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Top Ten most popular articles on Pharmafile.com this week

pharmafile | September 4, 2020 | News story | Medical Communications  

The top 10 news stories this week largely cover coronavirus, as Sanofi is halting clinical trials treating serious COVID-19 patients with its Kevzara drug after data on its efficacy proved inconclusive, while the US has said it will not participate in an international effort to develop and distribute a vaccine because it is linked to the WHO.

In other news, one teen has died after taking large amounts of the antihistamine Benadryl as part of a social media “challenge” on popular video site TikTok, and 20 Republican senators have sent a letter to the FDA urging them to take the abortion pill Mifeprex off the market.

1. Genexine’s cytokine drug effective in treating coronavirus patients, new study suggests

Genexine’s recent clinical trial investigating how its cytokine therapy treats coronavirus has proven effective, according to the company.

2. Oxford University’s COVID-19 vaccine begins Phase 3 trial in the US

AstraZeneca has started a Phase 3 trial of its experimental coronavirus vaccines in the US, making it the third company to start late-stage trials of a vaccine.

3. Novo Nordisk launches new Rybelsus pill for type 2 diabetes in the UK
Novo Nordisk’s new type 2 diabetes treatment Rybelsus is now available for doctors and physicians in the UK to prescribe to adult patients.

3. Novo Nordisk launches new Rybelsus pill for type 2 diabetes in the UK

Novo Nordisk’s new type 2 diabetes treatment Rybelsus is now available for doctors and physicians in the UK to prescribe to adult patients.

4. Four COVID-19 vaccine trials backed by Operation Warp Speed will likely fail, according to a new report

Four late-stage trials of vaccine candidates partly funded by the US Operation Warp Speed are likely to fail, according to a new report from medical experts.

5. Korea approves Celltrion’s Phase 1 trial of COVID-19 antiviral antibody treatment

Celltrion Group has announced that the Korean Ministry of Food and Drug Safety has approved the company’s Investigational New Drug application for a Phase 1 trial for their coronavirus antiviral antibody treatment candidate.

6. Sanofi halts Phase 3 trial of Kevzara as a COVID-19 treatment

Sanofi is halting clinical trials treating serious COVID-19 patients with its Kevzara drug after data on its efficacy proved inconclusive.

7. US won’t join COVAX coronavirus vaccine initiative because it is linked to the WHO

The US has said it will not participate in an international effort to develop and distribute a coronavirus vaccine.

8. J&J issues warning after teen dies from Benadryl TikTok challenge

One teen has died after taking large amounts of the antihistamine Benadryl as part of a social media “challenge” on popular video site TikTok.

9. NICE knocks back Janssen’s Spravato nasal spray for the second time in treatment-resistant depression

NICE has opted to reject Janssen’s nasal spray Spravato (esketamine) for routine use on the NHS for treatment-resistant major depressive disorder (MDD), following the drug’s second appraisal consultation with the UK watchdog.

10. Ted Cruz and 19 other GOP Senators ask FDA to remove Danco’s abortion drug Mifeprex from the market

Texas Senator Ted Cruz and 19 other senators have sent a letter to the FDA urging them to take the abortion pill Mifeprex off the market.

Conor Kavanagh

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