OSE Immunotherapeutics and Boehringer Ingelheim collaborate on cancer and cardio-renal-metabolic disease treatments
Betsy Goodfellow | May 24, 2024 | News story | Research and Development | Boehringer Ingelheim, Cancer, Cardiology, OSE Immunotherapeutics, cardio-renal-metabolic diseases
OSE Immunotherapeutics and Boehringer Ingelheim have announced a major expansion of their existing partnership. The expansion includes two new projects aiming to develop first-in-class treatments for the ongoing anti-SIRPα immune-oncology programmes.
The first additional project includes ‘an amendment of the existing collaboration and license agreement for the anti-SIRPα immuno-oncology compounds BI 765063 and BI 770371, which are being investigated in phase 1 clinical studies in advanced solid tumours, development will now also be pursued in cardiovascular-renal-metabolic (CRM) diseases’ and ‘a new preclinical programme will be launched to develop immune-cell activating treatments based on OSE’s cis-targeting anti-PD1/cytokine platform via an asset acquisition’, according to the press release.
Under the terms of the expansion to the agreement, OSE will receive an upfront payment of €13.5m and a potential €17.5m in milestone payments.
Clive R Wood, corporate senior vice president and global head of discovery research at Boehringer Ingelheim, commented: “We are very pleased to expand our pipeline of potential first-in-class CRM disease therapies, as well as our pipeline of first-in-class T-cell based anti-cancer therapies. The expansion of our partnership with OSE reflects our joint mission to improving patient outcomes in two of the biggest threats to global health.”
Betsy Goodfellow
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