New manufacturing products launched at Interphex
pharmafile | April 26, 2010 | News story | Manufacturing and Production |Â Â Interphex, manufacturing and production, manufacturing equipmentÂ
The annual Interphex exhibition in New York was somewhat low-key this year with attendance disrupted by the block on flights out of many European airports, but still served as a showcase for companies launching new manufacturing equipment. Here are some of the highlights.
Microfluidics introduced a new pharmaceutical processing system which could help companies shift from batch to continuous production of APIs. The Microfluidics Reactor Technology (MRT) device, simultaneously launched in the US and in Japan via a distribution agreement with Powrex, combines chemical crystallisation, nanoparticle creation and encapsulation technologies intone unit. “According to an independent 2010 survey that we commissioned, 80% of pharmaceutical companies plan to invest in continuous crystallisation technology,” said Microfluidics’ chief executive Michael Ferrara at the launch.
Pall Corp introduced what it claims is the industry’s first single-pass tangential flow filtration (TFF) system for downstream purification of biopharmaceuticals. The Cadence system eliminates the need to re-circulate material and allows direct flow operation which, along with improved recovery capabilities, yields product recoveries greater than 98%. The technology can be used for both single-use or re-use modes of operation.
Bosch Packaging launched two new machines at Interphex, the MHI 2020 automated vial filling and closing machine and the GKF 1400 ASB 100% capsule filler. The MHI 202 is designed for handling liquid pharmaceuticals in small batches, such as might be made for clinical trials and pilot production. The GKF 1400 ASB features production capacity of 84,000 capsules per hour, and an automatic troubleshooting module to increase output during production, plus an integrated checkweigher that allows for quick adjustment of fill weight to maintain consistent fill weight throughout a batch run.
O’Hara Technologies unveiled a new tablet-coating machine – the FASTCOAT Continuous Coater (Model FC C500) – which can coat more than 3,200kg of tablets within an eight-hour period when running in continuous mode. “The FC C500 can replace up to six production coaters with a single unit,” claimed O’Hara. The unit can also be run in batch mode.
Bioprocessing specialist ATMI unveiled a new disposable bioreactor at Interphex which it says “represents a … highly scalable entry point in its line of mixing and process manufacturing systems for the biopharma and biotech industries”. The Integrity PadReactor system accommodates reactor volumes ranging from 20 to 1,000 litres.
ShockWatch launched a new temperature monitoring device, the TempMark 8, designed to meet industry demands for ascending and descending temperature monitoring for pharmaceutical shipments. The device can be set up with up to eight temperature thresholds, and also features a built-in recorder to provide critical product data to manufacturers, handlers and receivers. Just the thing if your cold storage-critical shipment is grounded by an Icelandic volcano.
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