Merck scores expanded NICE recommendation in head, neck and oral cancer

pharmafile | August 8, 2017 | News story | Manufacturing and Production, Sales and Marketing Erbitux, Merck, NICE, biotech, cetuximah, drugs, life sciences, pharma, pharmaceuticals 

Merck has announced its approval of NICE’s decision to expand its recommendation of Erbitux (cetuximab) to include its use as a first-line treatment for recurrent or metastatic squamous cell carcinoma of the head and neck (SCCHN) of the oral cavity, when used in combination with platinum-based chemotherapy.

The institute had already recommended the drug in combination with radiotherapy for the treatment of SCCHN in patients who had a Karnofsky performance status of more than 90% and for whom platinum-based chemotherapy is contraindicated. The 0-100 scale provides a quantification of general well-being in cancer patients, with 100 representing ‘perfect’ health.

The drug was also recommended back in March this year in combination with platinum-based chemotherapy for the first-line treatment of RAS wild-type metastatic colorectal cancer (mCRC)

Advertisement

This new decision by NICE extends this recommendation beyond the locally advanced setting, and ensures that those affected in the oral cavity will have sustained access to a targeted treatment option.

 “We are delighted that patients with recurrent and/or metastatic head and neck cancer in the oral cavity will continue to have access to Erbitux and that NICE has recognised the survival benefit it can offer to patients with this disease,” Dr Belinda Byrne, Medical Director at Merck, UK said. “Merck has worked tirelessly with NICE throughout this review and its success illustrates our commitment to working in partnership with the National Healthcare Service and NICE.”

Matt Fellows

Related Content

Cellbyte raises $2.75m to fund pharma drug launch platform

Cellbyte has announced that it has raised $2.75m in seed funding for the streamlining of …

Lilly opens fourth US Gateway Labs site

Eli Lilly has opened its newest Lilly Gateway Labs (LGL) site in San Diego, California, …

Combination treatments: Takeda’s Implementation Framework and the broader landscape

Pharmafile talks to Emma Roffe, Oncology Country Head (UK & Ireland) about the combination treatment …

The Gateway to Local Adoption Series

Latest content