Shire's Adderall

Low Adderall sales hit Shire

pharmafile | February 22, 2010 | News story | Sales and Marketing 2009 financials, Adderall, Shire 

Shire has posted negative growth due to generic competition for its flagship ADHD drug Adderall XR.

Product sales were down 2% to $2.7 billion as Adderall sales dropped 43% to $627 million following the launch of generic versions by Teva in April and Impax in October 2009.

Excluding sales of Adderall XR, Shire’s core product sales were up 28% to $2.1 billion on a constant exchange rate basis.

Chief executive Angus Russell said: “Our growth prospects remain excellent and our core product portfolio currently has robust exclusivity protection. We have launched Intuniv successfully in the US; we plan to launch velaglucerase alfa (VPRIV) imminently, and there is also an opportunity for Replagal to enter the US market.

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“Vyvanse, our leading ADHD treatment with a current monthly US ADHD market share of 13.6%, continues to grow and build strong brand recognition in the US and has recently been launched in Canada. Adderall XR continues to generate value from both product sales and a considerable royalty stream.

“We have also demonstrated a pro-active approach to cost management in 2009 as promised, and have the opportunity to leverage our existing infrastructure to deliver expanding margins in the future.”

Shire has a number of potential product launches in 2010, pending regulatory review.

These include: Vpriv, indicated for the treatment of Gaucher’s disease; Replagal, for the treatment of Fabry disease; Equasym, for the treatment of ADHD in selected EU countries and Vyvanse, indicated for the treatment of ADHD in Canada.

Despite a full year loss, Russell said he remains confident that Shire will meet its target of mid-teen revenue growth on average between 2009 and 2015 on the strength of its pipeline.

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