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Abbvie acquires Cerevel Therapeutics

James Spargo | August 2, 2024 | News story | Mergers and Acquisitions AbbVie, Cerevel Therapeutics, Drug-Resistant Epilepsy, Neurology, Parkinson's disease, major depressive disorder, mergers & acquisitions, neurology, neuroscience, schizophrenia 

Abbvie has announced the acquisition of Cerevel Therapeutics, strengthening its neuroscience pipeline.

Cerevel has multiple programmes across neurological and psychiatric conditions such as schizophrenia, Parkinson’s disease and mood disorders. One example is emraclidine, a next-generation antipsychotic positive allosteric modulator (PAM) of the muscarinic M4 receptor, indicated for the treatment of schizophrenia. There is also tavapadon, a dopamine D1/D5 selective partial agonist for the management of Parkinson’s disease, which is currently in phase 3 studies.

Darigabat, an alpha 2/3/5 selective GABAA receptor PAM for the treatment-resistant epilepsy and panic disorder, is currently in phase 2, and CVL-354 – a kappa opioid receptor (KOR) antagonist currently in phase 1 – has the potential to provide improved efficacy and tolerability compared to existing treatments for major depressive disorder (MDD).

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“Abbvie’s acquisition of Cerevel strengthens our foundation in neuroscience and positions us to deliver sustainable long-term performance into the next decade and beyond,” said Robert A Michael, chief executive officer, AbbVie. “Our new Cerevel colleagues share our commitment to deliver meaningful change for patients living with neurological and psychiatric conditions. We are excited to welcome the talented Cerevel team to AbbVie.”

James Spargo

2/8/24

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