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Amgen’s novel KRAS inhibitor monotherapy shows promise at Phase 1 in advanced solid tumours

June 4, 2019
Manufacturing and Production, Research and Development, Sales and Marketing Amgen, Cancer, KRAS

Amgen has unveiled the first clinical data for its investigational KRAS inhibitor AMG 510, the first such therapy to reach …

News

EMA approves Bluebird Bio’s gene therapy Zynteglo

June 4, 2019
Manufacturing and Production Bluebird Bio, European comission, gene therapy, health, pharma

The European Commission has granted a conditional marketing authorisation to bluebird bio’s gene therapy Zynteglo. The Massachusetts-based firm’s one time …

News

Walmart join MediLedger medical supply chain blockchain network

June 3, 2019
Manufacturing and Production MediLedger, blockchain, medical supply chain, pharma

Walmart has joined the MediLedger network – a network of pharma firms who use a permissioned blockchain to manage the …

News

Working Life: Monika Pocinkova, Vice President, HR Speciality Care, Ipsen UK & Ireland

June 3, 2019
Business Services, Manufacturing and Production, Medical Communications, Research and Development, Sales and Marketing Working Life, feature, pharma

Ipsen’s Vice President of HR Speciality Care discusses the path she has taken throughout her career, the cultural differences she …

Feature
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Janssen’s Erleada combo smashes endpoints in advanced hormone-sensitive prostate cancer

June 3, 2019
Research and Development, Sales and Marketing ASCO 2019, Cancer, Erleada, Janssen, prostate cancer

Janssen joined the showing at the 2019 American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago to present new …

News

Isatuximab improves on standard of care treatments for multiple myeloma

June 3, 2019
Sales and Marketing Cancer, Immunogen, Sanofi, isatuximab, multiple myeloma, pharma

Sanofi and ImmunoGen’s isatuximab combination therapy prolonged progression free survival by five months compared to standard of care treatments in …

News
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Longest follow up trial of Merck’s Keytruda sets new standard for five year survival in lung cancer

June 3, 2019
Sales and Marketing KEYNOTE, MSD, Merck, keytruda, lung cancer

Nearly a quarter of previously untreated lung cancer patients who took Keytruda (Pembrolizumab) were alive after five years, according to …

News

Novartis’ Kisqali combo boosts survival in HR+/HER2- advanced breast cancer

June 3, 2019
Research and Development, Sales and Marketing Cancer, Kisqali, Novartis, breast cancer, pharma

Novartis took the opportunity at this year’s American Society of Clinical Oncology (ASCO) Annual Meeting to reveal new Phase 3 …

News

Healthcare would be ‘on the table’ in post-Brexit trade negotiations with US, Trump’s ambassador says

June 3, 2019
Sales and Marketing J&J, JJ, NHS, UK, US, brexit, healthcare

The American Ambassador to the United Kingdom has said that Britain’s healthcare system would be ‘on the table’ in post-Brexit …

News
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Dr Dietmar Berger returns to big pharma

May 31, 2019
Business Services, Manufacturing and Production, Medical Communications, Research and Development, Sales and Marketing Atara, R&D, Sanofi, oncology, pharma, research

Industry veteran Dr Dietmar Berger has joined Sanofi as the company’s new Global Head of Development. Dr Berger joins the …

Appointment
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Biogen’s diroximel fumarate impresses at Phase 3 in relapsing multiple sclerosis

May 31, 2019
Medical Communications, Research and Development Biogen, diroximel fumarate, multiple sclerosis, pharma, relapsingg multiple sclerosis

New data for Biogen’s investigational therapy diroximel fumarate has been revealed at the Consortium of Multiple Sclerosis Centers (CMSC) in …

News
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Top Ten most popular articles on Pharmafile.com this week!

May 31, 2019
Business Services, Manufacturing and Production, Medical Communications, Research and Development, Sales and Marketing China, FDA, GSK, Novartis, Pfizer, environment, opioids, pharma, pricing

The pharmaceutical industry is a big polluter than the automotive industry. This was our top story this week. The findings …

News
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RCP calls on NICE to update guidelines on coming off antidepressants

May 31, 2019
Medical Communications Guidelines, NICE, RCP, antidepressants, health, pharma

Guidance for patients on coming off antidepressants needs to be updated, according to the Royal College of Psychiatrists (RCP). Current …

News
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NICE recommends MSD’s Prevymis for CMV prevention following allogeneic haematopoietic stem cell transplant

May 31, 2019
Medical Communications, Sales and Marketing MSD, NICE, Prevymis, UK, cmv, cytomegalovirus, pharma

MSD has revealed that its non-nucleoside CMV inhibitor Prevymis (letermovir) has secured recommendation from NICE, meaning it will now be …

News
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Synthetic, non-intoxicating CBD analogue treats seizures in rats

May 31, 2019
Medical Communications CBD, H2CBD, cannabidiol, medicinal cannabis, pharma

A synthetic, non-intoxicating cannabidiol (CBD)-analogue is effective at treating seizures in rats, according to researchers at the University of California, …

News
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Investigational Novartis therapy smashes primary and secondary endpoints in uncontrolled asthma

May 30, 2019
Research and Development Novartis, QVM149, asthma, pharma

Novartis has announced the first findings on the efficacy of its investigational asthma therapy QVM149 in the treatment of inadequately …

News
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Long term BMS exec Johanna Mercier joins Gilead as new Chief Commercial Officer

May 30, 2019
Medical Communications, Sales and Marketing BMS, Bristol-Myers Squibb, Gilead, cco, commercial, pharma

Gilead Sciences have said Bristol-Myers Squibb exec Johanna Mercier will be the firm’s new Chief Commercial Officer. In her new …

News
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Novo Holdings invests £53.5 million into Oxford Biomedica

May 30, 2019
Business Services, Sales and Marketing Novo Holdings, Novo Nordisk, Oxford BioMedica, Shares, cell and gene therapy, lentivirus

Novo Holdings has agreed to buy 10.1% of shares in British firm Oxford Biomedica for £53.5 million. Novo will buy …

News
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Janssen presents strong Phase 3 showing for Darzalex in multiple myeloma subgroup

May 30, 2019
Research and Development Janssen, darzalex, pharma

Janssen has lifted the curtain on new Phase 3 data for Darzalex (daratumumab) in combination with lenalidomide and dexamethasone (Rd), …

News

Oklahoma prosecutors say J&J used ‘brainwashing campaign’ to boost opioid sales

May 30, 2019
Research and Development J&J, JJ, opioid crisis, opioids, pharma, public health

Oklahoma state prosecutors have accused Johnson & Johnson of engaging in a “cynical, deceitful, multibillion-dollar brainwashing campaign” to boost sales …

News
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