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Merck KGaA and Pfizer’s Bavencio falls short in ovarian cancer

November 20, 2018
Manufacturing and Production, Research and Development Bavencio, Cancer, Merck MGaA, Pfizer, ovarian cancer, pharma

Merck KGaA and Pfizer’s Bavencio (avelumab) has missed its primary endpoints in the treatment of platinum-resistant or -refractory ovarian cancer, …

News

Pfizer to resume price hiking in 2019; 41 drugs set to increase

November 20, 2018
Manufacturing and Production, Sales and Marketing Pfizer, Trump, pharma, price hikes, price hiking, pricing

American pharma firm Pfizer has revealed plans to increase the prices of 41 medicines, the equivalent of 10% of its …

News
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Eli Lilly’s Emgality cleared for treatment of migraine in Europe

November 20, 2018
Manufacturing and Production, Sales and Marketing EU, Eli Lilly, Emgality, Europe, migraine, pharma

Eli Lilly’s Emgality (galcanezumab) has secured approval from the European Commission for the prophylaxis of migraine in adult patients who …

News

Novartis’ Promacta cleared by FDA for first-line use in severe aplastic anaemia

November 19, 2018
Sales and Marketing FDA, Novartis, Promacta, Revolade, US, aplastic anaemia, pharma

Novartis has secured expanded approval from the FDA for Promacta (eltrombopag), allowing it to now be used in combination with …

News
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Mundipharma name GSK veteran as new Senior Vice President & CFO

November 19, 2018
Business Services, Manufacturing and Production, Medical Communications, Research and Development, Sales and Marketing Cambridge, Mundipharma, arnaud breabout, cfo, svp, wsenior vice president

The Mundipharma network today confirmed the appointment of Arnaud Breabout, to the position of Senior Vice President & Chief Financial …

Appointment
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Roche withdraws Tecentriq combo application in first-line renal cell carcinoma

November 19, 2018
Sales and Marketing Cancer, Roche, avastin, pharma, renal cell carcinoma, tecentriq

The EMA has revealed that Roche has chosen to withdraw its marketing application for immunotherapy Tecentriq (atezolizumab) in combination with …

News
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EU rules may be stifling Britain’s biotech industry

November 19, 2018
Sales and Marketing EU, biotech, britain, funding, grants, industry

EU rules are stifling Britain’s biotech industry, according to companies who talked to British newspaper The Daily Telegraph. The newspaper …

News

MSD’s Keytruda to treat melanoma in England on the Cancer Drugs Fund

November 19, 2018
Sales and Marketing England, MSD, NHS, UK, keytruda, melanoma, pharma

MSD’s blockbuster immunotherapy Keytruda (pembrolizumab) will now be made available to patients in England via the Cancer Drugs Fund, it …

News
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FDA trial may help to cut the number of dogs used in clinical trials

November 19, 2018
Sales and Marketing Animal testing, animal activists, clinical trials, dogs, health, tests

A new study may help to significantly reduce the number of dogs that are used in clinical trials, according to …

News
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Alector strengthens board with three appointments including Facebook CFO David Wehner

November 16, 2018
Business Services, Manufacturing and Production, Medical Communications, Research and Development, Sales and Marketing

Facebook’s Chief Financial Officer (CFO) David Wehner has joined the board of San Francisco-based biotech Alector, a company that hopes …

Appointment
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AstraZeneca’s Imfinzi immunotherapy combo fails to show benefit in lung cancer

November 16, 2018
Medical Communications, Research and Development AstraZeneca, Cancer, Imfinzi, lung cancer, pharma

AstraZeneca has revealed that its immunotherapy combo of Imfinzi (durvalumab) and tremelimumab failed to meet its primary endpoint in a …

News
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Top Ten most popular articles on Pharmafile.com this week!

November 16, 2018
Business Services, Manufacturing and Production, Medical Communications, Research and Development, Sales and Marketing Korea, NICE, Samsung, Theresa May, UK, brexit, politics, top 10

The Samsung scandal played a prominent role in this weeks’ top ten after the South Korean firm was delisted from …

News
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Boehringer signs $300 million deal with Epizyme over epigenetic cancer treatment

November 16, 2018
Medical Communications Boehringer, Cancer, Epizyme, deal, oncology

German firm Boehringer Ingelheim and the Massachusetts-based biotech Epizyme have announced that they will collaborate on the development of novel, …

News
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United Therapeutics buys Arena’s hypertension drug ralinepag in deal worth $1.2 billion

November 16, 2018
Medical Communications Arena, PAH, United Therapeutics, deal sales, hypertension

US pharma firm United Therapeutics has agreed to by Arena Pharmaceuticals experimental pulmonary arterial hypertension (PAH) drug ralinepag in a …

News
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Ipsen’s Cabometyx gains European approval in hepatocellular carcinoma

November 16, 2018
Medical Communications, Sales and Marketing Cabometyx, carcinoma, ipsen, pharma. European Commission

Ipsen’s Cabometyx has received approval from the European Commission for Cabometyx (cabozantinib) as a monotherapy for the treatment of hepatocellular …

News
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Dermavant appoint Todd Zavodnick as CEO

November 15, 2018
Business Services, Manufacturing and Production, Medical Communications, Research and Development, Sales and Marketing

Roivant subsidiary Dermavant has appointed experienced pharma exec Todd Zavodnick as the company’s new CEO. The Rutger’s University graduate will …

Appointment
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Rising to the challenge of delivering therapeutic discovery for mental disorders

November 15, 2018
Business Services, Manufacturing and Production, Medical Communications, Research and Development, Sales and Marketing NIHRm, Oxford, R&D, feature, investment, mental health

Professor Matthew Hotopf, Director of NIHR Maudsley Biomedical Research Centre, and Professor John R Geddes, Director of NIHR Oxford Health …

Feature

Kymriah to be made available in UK for paediatric leukaemia patients via Cancer Drugs Fund

November 15, 2018
Sales and Marketing CAR-T, Cancer, Cancer Drugs Fund, Kymriah, NHS, NICE, leukaemia, pharma

NICE has announced its recommendation that Novartis’ CAR-T cell therapy Kymriah (tisagenlecleucel) be made available in the treatment of relapsed …

News
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MSD’s Keytruda improvess overall survival in Phase 3 oesophageal cancer

November 15, 2018
Research and Development Cancer, MSD, PD-L1, keytruda, pharma

MSD has announced new Phase 3 data on its anti-PD-1 therapy Keytruda (pembrolizumab) as a second-line treatment for advanced or …

News
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Phamaceutical trade lobby responds to Brexit deal

November 15, 2018
Business Services, Medical Communications, Research and Development ABPI, brexit, negotiations, pharma, politics

The Association of the British Pharmaceutical Industry (ABPI) has responded to Theresa May’s Brexit deal, after the government announced a …

News
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