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AstraZeneca vaccine found to be 3% less effective after further trial analysis

March 25, 2021
AstraZeneca, AstraZeneca vaccine, COVID-19, COVID-19 vaccine, Vaccine

AstraZeneca have revised their findings from the US study AZD1222 of their COVID-19 vaccine, announcing a 76% efficacy against symptoms …

News

NHS agrees on MSD interim colorectal cancer treatment

March 25, 2021
COVID-19, Cancer, MSD, NHS

MSD has announced a provisional agreement with the NHS to make KEYTRUDA (pembrolizumab) available for eligible patients with metastatic MSI-H/dMMR …

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AstraZeneca and J&J COVID-19 vaccines face viral vector shortage

March 25, 2021
Astrazenaca, COVID-19, Johnson & Johnson, Vaccine

Both AstraZeneca and J&J face major manufacturing deficiencies for their recombinant vector COVID-19 vaccines, forcing competition over limited production capacity …

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COVID-19 virus

Pharmafile.com’s weekly COVID-19 news round-up

March 24, 2021
Research and Development COVID-19, covid 19 news, covid-19 news, news roundup

The past week has seen plenty of positive COVID-19 news; the Oxford-AstraZeneca vaccine was deemed safe and effective by the …

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Roche’s drug cocktail reduces hospitalisation due to COVID-19 in Phase III trial

March 24, 2021
Research and Development COVID-19, Roche, covid-19 treatment

Roche’s antibody drug combination of casirivimab and imdevimab has shown to reduce hospitalisation or death by 70% in non-hospitalised patients …

News

Pfizer and Myovant’s menstrual blood loss treatment reports 78% effectiveness

March 24, 2021
Research and Development Myovant, Pfizer, Phase III trial, fibroids, uterine fibroids

Pfizer and Myovant Science’s relugolix treatment to reduce menstrual blood loss in women with uterine fibroids has shown promising results …

News

Novo Nordisk obesity treatment successful in clinical trials

March 24, 2021
Research and Development Novo Nordisk, obesity

New results from Novo Nordisk’s Phase III study on obesity saw clinically relevant weight loss, without weight regain, in people …

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Guerbet see positive Phase III results for MRI agent

March 24, 2021
Research and Development MRI

Medical imaging company, Guerbet, have announced the success of its Phase III study into the safety and efficacy of Gadopiclenol, …

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Zealand’s Zegalogue treatment for hypoglycemia approved by FDA

March 23, 2021
Manufacturing and Production FDA, Zealand Pharma, Zegalogue

The FDA have approved Zealand Pharma’s Zegalogue therapy for the treatment of severe hypoglycemia in patients with diabetes.

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Incyte biliary tract cancer treatment approved in Japan

March 23, 2021
Manufacturing and Production EMA, Japan, oncology

The Japanese Ministry of Health, Labour, and Welfare (MHLW) have approved Incyte’s Pemazyre (pemigatinib) for the treatment of patients with …

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Accord Healthcare launches thalidomide for multiple myeloma treatment

March 23, 2021
Manufacturing and Production MHRA, oncology

Accord Healthcare has announced the UK launch of a generic thalidomide, which is used in combination with melphalan and prednisone, …

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Roche’s Huntington’s disease treatment disappoints in Phase III trial

March 23, 2021
Manufacturing and Production Huntington's, Phase III trial, Roche, huntington's disease, tominersen

Roche has discontinued dosing in a Phase III trial of its tominersen treatment for Huntington’s disease, following discouraging initial data.

News

Novartis prostate cancer treatment sees positive Phase III results

March 23, 2021
Manufacturing and Production Novartis, oncology

Novartis has today announced positive results from its Phase III VISION study with 177Lu-PSMA-617, seeing significant improvements in overall survival …

News

eTheRNA awarded €6.9 million TIGER Grant by European Commission

March 22, 2021
Sales and Marketing Cancer, EU

eTheRNA immunotherapies, a clinical-stage company, has been awarded a grant of €6.9 million by the European Commission to develop a …

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Daiichi Sankyo begins trial for mRNA COVID-19 vaccine in Japan

March 22, 2021
Sales and Marketing COVID-19, Vaccine

Daiichi Sankyo, a global pharmaceutical company that provides services in 20 countries worldwide, has announced the first vaccinations as part …

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FDA approves Kiniksa’s recurrent pericardis treatment ARCALYST

March 22, 2021
Sales and Marketing FDA

The FDA have approved ARCALYST (rilonacept) for the treatment and risk reduction of recurrent pericardis in adults and children over …

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Roche lung cancer treatment reports promising results in Phase III

March 22, 2021
Sales and Marketing Roche, oncology

Roche’s IMpower010 study, evaluating Tecentriq (atezolizumab) compared with best supportive care, has shown significant improvement in disease-free survival (DFS) in …

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AstraZeneca COVID-19 vaccine achieves safety and efficacy results in US

March 22, 2021
Sales and Marketing

Results from the US trial of AstraZeneca’s COVID-19 vaccine (AZD1222) show it is 79% effective at stopping symptomatic COVID-19 disease …

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Pharmafile.com’s top 10 news stories of the week

March 19, 2021
Medical Communications COVID, COVID-19, covid 19 news, covid-19 news, news, news roundup, pharma news

In the last week, a number of new developments have made the news; for COVID-19, the Oxford-AstraZeneca vaccine has been …

News

RDIF & Stelis Biopharma to supply 200 million doses of the Sputnik V vaccine

March 19, 2021
Medical Communications COVID-19, Russia, Vaccine

The Russian Direct Investment Fund (RDIF) and Stelis Biopharma have today announced a partnership which aims to produce and supply …

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